An observative study of comparision between non-antibiotic and antibiotic treatment of acute diarrhea in a tertiary hospital.
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2019, Vol 8, Issue 1
Abstract
Background Acute diarrhoeal diseases rank among one of the most common infectious disease in almost all age groups worldwide.. Antibiotic therapy is not recommended for the treatment of diarrhoea routinely, only severe cases should be treated with a suitable antibiotic. Because of paucity of published reports in the Indian literature regarding the pattern of use of antibiotics in treatment of acute diarrheal cases, the present study was taken up. Objectives To study the comparison of treatment of acute diarrheal cases with or without antibiotic, in terms of outcome, safety and tolerability. Materials and Methods 100 properly selected subjects with acute diarrhea were included for the present study. The medications were used orally or intravenously for 5-7 days, depending upon the particular case. The treatment outcome was assessed by noting number of diarrhea and vomiting episodes, pulse, blood pressure, weight and skin pinch of the patient from day 1 till the infection resolve completely. The data collected was analyzed statistically using descriptive statistics. Tolerability and patient compliance for the prescribed medications were also assessed during the follow up visits. Results Most of the subjects showed complete resolution of episodes of diarrhea and vomiting, with normalization of blood pressure by 2nd day and all subjects by end of 5th day with a minor majority in non-antibiotic treatment. Interpretation and Conclusion The acute diarrheal cases can be effectively treated by empirical use of non-antibiotics medications itself. Antibiotics are reserved for particular cases only.
Authors and Affiliations
Dr. Syed Wasif
Keywords
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