An Overview of The Globozoospermia as A Multigenic Identified Syndrome
Journal Title: International Journal of Fertility & Sterility - Year 2019, Vol 12, Issue 4
Abstract
Acrosome plays an integral role during fertilization and its absence in individuals with globozoospermia leads to failure of in vitro fertilization (IVF) and oocyte activation post-intracytoplasmic sperm injection (ICSI). A variety of processes, organelles and structures are involved in acrosome biogenesis including, trans-golgi network (TGN), acroplaxome and cellular trafficking. This review aims to explain roles of related signals and molecules involved in this process and also describe how their absence in form of mutation, deletion and knockout model may lead to phenomenon referred to globozoospermia.
Authors and Affiliations
Parastoo Modarres, Marziyeh Tavalaee, Kamran Ghaedi
Keywords
Related Articles
- EP ID EP469169
- DOI 10.22074/ijfs.2019.5561
- Views 221
- Downloads 0
Evaluating The Effective Factors in Pregnancy after Intrauterine Insemination: A Retrospective Study
Background Controlled ovarian hyperstimulation (COH) in conjunction with intrauterine inseminations (IUI) are commonly used to treat infertile couples. In this study we evaluated the relationship between IUI outcome and...
Investigation of Personality Traits between Infertile Women Submitted to Assisted Reproductive Technology or Surrogacy
Background Personality traits affect human relationships, social interactions, treatment procedures, and essentially all human activities. The purpose of this study is to investigate the personality traitsincluding sensa...
Outcomes after Hysteroscopic Treatment of Symptomatic Isthmoceles in Patients with Abnormal Uterine Bleeding and Pelvic Pain: A Prospective Case Series
Background Isthmoceles are described as complications associated with caesarean section (CS). Only symptomatic isthmoceles should be treated. The main symptoms are abnormal uterine bleeding (AUB) in the absence of any ot...
Quality of Life and Its Influencing Factors of Couples Referred to An Infertility Center in Shiraz, Iran
Background Infertility adversely affects quality of life (QoL). The present study aims to evaluate QoL and its associ- ated factors among infertile couples. Materials and Methods In this cross-sectional study, the Ferti...
Dietary Phytoestrogen Intake and The Risk of Endometriosis in Iranian Women: A Case-Control Study
Background: Endometriosis is an important gynecologic disease affecting reproductive-age women. Based on the effect of phytoestrogens on inflammatory, immunological and hormonal factors, limited studies have suggested th...