AN OVERVIEW ON VARIOUS APPROACHES TO ORAL CONTROLLED DRUG DELIVERY SYSTEM VIA GASTRORETENTIVE DRUG DELIVERY SYSTEM
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 4
Abstract
In recent years scientific and technological advancements have been made in the research and development of oral drug delivery system. Oral sustained drug delivery system is complicated by limited gastric residence times (GRTs). In order to understand various physiological difficulties to achieve gastric retention, we have summarized important factors controlling gastric retention. To overcome these limitations, various approaches have been proposed to increase gastric residence of drug delivery systems in the upper part of the gastrointestinal tract includes floating drug dosage systems (FDDS), swelling or expanding systems , mucoadhesive systems , magnetic systems, modified-shape systems, high density system and other delayed gastric emptying devices.
Authors and Affiliations
Neetika Bhalla. , Arsh Deep , Manish Goswami
Keywords
Related Articles
- EP ID EP92654
- DOI -
- Views 96
- Downloads 0
SIMULTANEOUS ESTIMATION OF ROSUVASTATIN CALCIUM AND CLOPIDOGREL BISULPHATE FROM BULK AND COMMERCIAL PRODUCTS USING A VALIDATED REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC TECHNIQUE
A simple, rapid, accurate, precise and economical reverse phase high performance liquid chromatographic method is developed for simultaneous separation and quantification of two cardiovascular drugs, viz., Rosuvastatin C...
PHYSICIANS' KNOWLEDGE, ATTITUDES AND PRACTICE ABOUT THE TREATMENT OF HIGH BLOOD PRESSURE ACCORDING TO THE SEVENTH REPORT OF THE JOINT NATIONAL COMMITTEE (JNC VII)
Hypertension is one of the most frequently encountered chronic medical conditions in almost all societies. The Seventh Report of the Joint National Committee (JNC-7), published in 2003 is an important tool on Detection,...
IMPORTANT FINDINGS ON PLANTS HAVING ANTIOXIDANT PROPERTY: A REVIEW
Plants have certain biologically active molecules and many of the present drug discoveries are based on these molecules found in the plants used in traditional system of medicine. In this review paper 20 plants (Emblica...
EVALUATION OF GLYCOLIPIDS OF SOME EGYPTIAN MARINE ALGAE AS A SOURCE OF BIOACTIVE SUBSTANCES
Glycolipids in five species of marine algae: two species of Rhodophyta (Laurencia popillose, Galaxoura cylindriea); and one species of Chlorophyta (Ulva fasciata), and two species of Phaeophyta (Dilophys fasciola, Taonia...
PREFORMULATION STUDIES OF CONTROLLED/SUSTAINED RELEASE FORMULATIONS: AN OVERVIEW
Recently, controlled release drug delivery has become the standards in the modern pharmaceutical design and intensive research has been undertaken in achieving much better drug product effectiveness, reliability and safe...