An Unusual Case of Primary Plasma Cell Leukaemia Mimicking Acute Leukaemia: A Case Report and Review of Literature
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 12
Abstract
Plasma Cell Leukaemia (PCL) is rare and an aggressive disease accounting for only 2-3% of all plasma cell dyscrasias. Diagnosis is made when there are more than 2x109 /L plasma cells in the peripheral blood or monoclonal plasmacytosis more than 20% of the Total Leucocyte Count (TLC). We report a case of 58-year-old male with history of high grade fever, generalized weakness and giddiness for two to three months. Peripheral blood film revealed marked leucocytosis with 88% of atypical cells resembling blasts. Flow cytometric immunophenotyping confirmed plasmacytic lineage. Bone marrow was planned but the patient deteriorated very rapidly and died within 3 days. PCL has no definitive treatment and has a dismal prognosis, requiring more extensive data to improve the disease course.
Authors and Affiliations
Abha Singla, Monica Gupta
Keywords
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- EP ID EP368109
- DOI 10.7860/JCDR/2017/31003.10948
- Views 27
- Downloads 0
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