An Unusual Neurological Syndrome of Hypothyroidism
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 8
Abstract
Neurological manifestations of hypothyroidism are not usually seen early in the course of the disease, particularly muscle disease. Entrapment neuropathy is more common and may be a presenting symptom. Hypothyroidism presenting as muscle stiffness and pseudohypertrophy in adults is known as Hoffman’s syndrome which is supported by presence of elevated CPK and EMG features of myopathy, neuropathy or mixed pattern. With hormone replacement therapy symptoms and CPK levels normalize promptly. We report a case of hypothyroidism with extreme muscle pain, calf muscle hypertrophy as initial symptoms.
Authors and Affiliations
Dr H Subramony
Keywords
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