An Unusual presentation of Gastric Gastro intestinal Stromal Tumour: A Case Report
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 6
Abstract
Gastro-intestinal stromal tumours (GIST) are uncommon malignancies of the gastro-intestinal tract and can occur in any part of the alimentary canal , from esophagus to anus. The most common sites of presentation are stomach, small bowel and rectum.95% of GIST are positive for KIT (CD117) and Platelet Derived Growth factor Receptor Alpha (PDGFRA). Treatment of choice is complete surgical excision with negative margins (R0 resection). A 68 years old male presented with slowly progressive abdominal lump in the right iliac fossa. CECT abdomen suggestive of hypervascular heterogenous mass arising from pelvis with low central attenuation with no distant metastasis. Patient was taken up for exploratory laparotomy and intra operatively it was found to be a huge exophytic, well circumscribed tumour arising from the lesser curvature of stomach , complete surgical resection was done. Microscopically diagnosis of gastric GIST of spindle cell morphology was found which was strongly positive for DOG1/CD34 and immunonegative for CD117. Medical oncology reference was taken on follow up and patient was started on imatinib therapy. This case report sites a rare presentation of gastric GIST in right iliac fossa with inconclusive CT reports. So a high index of suspicion must be kept in mind for diagnosing such rare tumours
Authors and Affiliations
Waqar Ahmed Ansari
Keywords
Related Articles
- EP ID EP512498
- DOI -
- Views 71
- Downloads 0
Mucocele of the Appendix
Mucocele is a rare entity of the appendix associated with either neoplastic or non-neoplastic mucinous lesions of the appendix. Understanding the pathology and natural history is essential for early diagnosis and prompt...
Correlation between Doppler and Perinatal Outcome in IUGR Babies
Introduction: Intrauterine growth retardation refers to a rate of growth of a fetus that is less than normal for the growth potential of a fetus (for that particular gestational age). IUGR affects 26 % of our population...
Colon Surgery with & without Mechanical Bowel Preparation: A Comparative Study
Mechanical bowel cleansing is part of routine preoperative preparation of patients planned for colectomy worldwide. The commonly used bowel preparation agent is polyethylene glycol, but this drug causes severe morbidity....
Aerobic Bacteriological Profile of Post-Operative Surgical Wound Infections and Their Antibiogram in A Tertiary Care Hospital
Background And Objectives: Post-operative wound infections are considered as the commonest nosocomial infections after urinary tract infections and are responsible for the increasing cost, morbidity and mortality prolong...
Characterization of Candida Species isolated from samples taken from patients with known Immunocompromised state presenting with Oral Thrush
Introduction: Oral thrush caused by Candida species is mostly an opportunistic infection. Candida albicans is known to be the major cause of the infection, however, over the last few decades several authors have reported...