An Unusual presentation of Gastric Gastro intestinal Stromal Tumour: A Case Report
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 6
Abstract
Gastro-intestinal stromal tumours (GIST) are uncommon malignancies of the gastro-intestinal tract and can occur in any part of the alimentary canal , from esophagus to anus. The most common sites of presentation are stomach, small bowel and rectum.95% of GIST are positive for KIT (CD117) and Platelet Derived Growth factor Receptor Alpha (PDGFRA). Treatment of choice is complete surgical excision with negative margins (R0 resection). A 68 years old male presented with slowly progressive abdominal lump in the right iliac fossa. CECT abdomen suggestive of hypervascular heterogenous mass arising from pelvis with low central attenuation with no distant metastasis. Patient was taken up for exploratory laparotomy and intra operatively it was found to be a huge exophytic, well circumscribed tumour arising from the lesser curvature of stomach , complete surgical resection was done. Microscopically diagnosis of gastric GIST of spindle cell morphology was found which was strongly positive for DOG1/CD34 and immunonegative for CD117. Medical oncology reference was taken on follow up and patient was started on imatinib therapy. This case report sites a rare presentation of gastric GIST in right iliac fossa with inconclusive CT reports. So a high index of suspicion must be kept in mind for diagnosing such rare tumours
Authors and Affiliations
Waqar Ahmed Ansari
Keywords
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