An update on hypoxic regulation of iron homeostasis and bone marrow environment
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 10
Abstract
Iron is very important in the body especially for effective erythropoiesis and should be maintained at a normal level. Some disease conditions may precipitate increased or decreased levels of iron. The body has some iron regulatory proteins which ensure stability in the balance between storage iron and circulatory iron. The availability of sufficient amounts of iron is critically important for normal and stress-induced erythropoiesis. Serum iron levels depend on intestinal absorption from the diet, transport capacity in the blood, recycling of iron released from phagocytosed erythrocytes, and the release of iron from other tissue stores, such as the liver. This paper is written to review the regulation of iron in bone marrow environment.
Authors and Affiliations
Obeagu E. I. Okoroiwu I. L. Azuonwu O.
Keywords
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- EP ID EP549404
- DOI 10.22192/ijcrms.2018.04.10.007
- Views 163
- Downloads 0
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