Analgesic Activity of Asoka – Saraca asoca (Roxb.) de Wilde
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 9
Abstract
The drug, Asoka – Saraca asoca (Roxb.) de Wilde. has been included under Vedanasthapana Mahakashaya mentioned in Shatvirechana shatasriteeya by Acharya Charaka. Analgesic activity of drug has been mentioned in the classics. It is extensively used as arishta in the management of various anila vedana in Udavartha. In order to ascertain the pharmacology of analgesic action this study has been done in a reverse pharmacological aspect. Analgesic activity has been assessed using acetic acid induced writhing method in female Wistar Albino rats. The writhing syndrome was established by intra peritoneal injection of 0.25% v/v acetic acid in normal saline (0.4ml/ 200g b.wt.). The test drug and standard drug, will be administered to rats 60 minutes prior to injection of acetic acid. The analgesic activity is expressed as percent inhibition of writhing. Analgesic study was found significant in effective and double effective dose of the test drug compared to control. Thus, it confirms the analgesic activity of kashaya of stem bark of Asoka – Saraca asoca (Roxb.) de Wilde.
Authors and Affiliations
Asha S Raj
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