Analysing false negatives and false positives in cytopathology of breast masses along with cytohistopathological correlation
Journal Title: IP Archives of Cytology and Histopathology Research - Year 2018, Vol 3, Issue 3
Abstract
Introduction Carcinoma of the breast is the leading cause of death in women due to malignancy Approximately 1000000 cases occur worldwide annually Evaluation of the breast masses is of utmost important for its timely management Fine needle aspiration cytology is a simple and reliable diagnostic method The present study aim ED to determine the diagnostic efficacy of the fine needle aspiration cytology along with evaluating the causes of false negative and false positive in breast cytologyMaterials and Methods The present retrospective study was conducted in G K General Hospital Bhuj for a period of one year Cases in which follow up histopathology was available were only included in the present study A total 52 cases were included in the studyResults Fine needle aspiration cytology findings and histopathology diagnoses were correlated Statistical analysis was done Out of the 52 cases only one false positive and one false negative case was found Hence the sensitivity of the study was 98 and the positive predictive value was also 98Conclusion Fine needle aspiration cytology is a reliable diagnostic method to evaluate the breast masses A high sensitivity and a high positive predictive value proved that a positive fine needle aspiration cytology in the breast correlates very well with the corresponding final histopathology reports Keywords Fine needle aspiration cytology Sensitivity Positive predictive value
Authors and Affiliations
Riti Sinha, Nutan Patel, Navin Patel
Keywords
Related Articles
- EP ID EP490577
- DOI 10.18231/2456-9267.2018.0030
- Views 104
- Downloads 0
Cytodiagnosis of primary intraosseous squamous cell carcinoma of left mandible with unusual finding
Primary intraosseous carcinoma of mandible originating as a de-novo is a rare neoplastic entity. Its origin thought to be from previous odontogenic cyst or de novo rather than pre formed epithelia lesion. It presumed to...
The study of vesicobullous skin lesions by Tzanck smear cytology
Vesicobullous lesion of skin and mucosa is commonly seen in clinical practice of dermatology Tzanck smear preparation is simple sensitive rapid and inexpensive procedure that has capacity to reveal the cytomorphological...
Morphologic spectrum of gastrointestinal polyps and polypoid lesions - A five year study
Introduction Polyps begin as small elevations of the mucosa and polyps are most common in the colorectal region The neoplastic polyps are important because they have a risk of transformation into malignancy The role of t...
Impact of major life style factors on male fertility in rural based population
Background: Infertility is the inability of the couples to conceive after 12 months of unprotected intercourse. There are innumerable causes of infertility including lifestyle factors. This study was to determine the spe...
Significance and Incidence of KRAS Mutations in Colorectal Carcinoma and Precancerous Lesions-A Retrospective Study in a Tertiary Care Centre
Introduction: KRAS mutation occurs in colorectal cancers in about 35%-45% cases. Colorectal carcinoma develops from precursor lesions and KRAS mutations occur early in carcinogenesis. KRAS mutation status can help to pre...