Analysis of adverse events following immunization of adsorbed acellular DPT vaccine at different vaccination sites
Journal Title: Shanghai Journal of Preventive Medicine - Year 2023, Vol 35, Issue 3
Abstract
ObjectiveTo analyze the occurrence of suspected adverse events following immunization ï¼AEFIï¼ after changing the priority vaccination sites of the adsorbed acellular diphtherior-pertussis-tetanus vaccine ï¼hereinafter referred to as DPT vaccineï¼ï¼ so as to provide scientific basis for mass vaccination.MethodsMonitoring data of AEFI for the DPT vaccine in Wujiang District from September 2020 to August 2022 were collected from China's disease prevention and control information systemï¼ and the vaccination information of DPT vaccine in all children's vaccination clinics in Wujiang District during the same period was selected. The incidence of AEFI for the DPT vaccine was analyzed and compared.ResultsThe reported incidence of AEFI was significantly lower in the buttocks than that in other sites ï¼P<0.05ï¼. The reported incidence of AEFI was significantly higher in booster immunization than that in basic immunization ï¼P<0.05ï¼. After inoculation at different sitesï¼ the main clinical symptoms of AEFI were local redness and swelling. There were significant differences in the incidence of local redness and swellingï¼ local indurationï¼ pruritus and other symptoms ï¼lethargyï¼ abnormal cryingï¼ etc.ï¼ ï¼P<0.05ï¼. There were significant differences in the severity of local redness and swelling in different sites ï¼P<0.05ï¼. The degree of redness and swelling in the anterolateral thigh was lower than that in other sites ï¼P<0.05ï¼. The local strong reaction of swelling ï¼>5.0 cmï¼ in the deltoid muscle of the upper arm was significantly higher than that in the buttocks ï¼P<0.05ï¼.ConclusionThe DPT vaccine is safe in different parts of the body and is worth popularizing.
Authors and Affiliations
SHEN Min,LIU Cunfang,QIAN Yidan,LU Zhirong,
Keywords
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