Analysis of Cathinone and Cathine in Urine Sample of Khat Chewer Presenting with Hemorrhagic Stroke
Journal Title: Journal of Gynecology and Neonatal Biology - Year 2018, Vol 3, Issue 1
Abstract
Khat contains cathinone and cathine, which are known to be associated with myocardial infarction and cerebral hemorrhage. Thereis limited data showing a relationship between khat chewing and hemorrhagic stroke. In Jazan region, the most of stimulant toxicity cases were toxicated by both khat and amphetamine. This report represents a khat chewer whose toxicity was only suspected to be from khat chewing. Thelevels of cathine and cathinone in the blood and urine samples of a khat chewer were determined. The method of extraction and analysis were discussed. The results of initial analysis were negative for amphetamine, cocaine, opiate, barbiturate and tricycle antidepressant. The urine initial analysis results were positively for amphetamine like substance. On further investigation, the confirmatory analysis by liquid chromatography-tandem mass spectrometry LC-MS/MS in urine were detected and quantified cathine and cathinone.
Authors and Affiliations
Attafi M. I
Keywords
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- EP ID EP428929
- DOI 10.15436/2575-808X/18.1868
- Views 96
- Downloads 0
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