Analysis of Chemical Compounds and Antibacterial Effect of Five Medicinal Plant Essential Oils on Infectious Bacteria

Apply

Analysis of Chemical Compounds and Antibacterial Effect of Five Medicinal Plant Essential Oils on Infectious Bacteria

Journal Title: Trends in Pharmaceutical Sciences - Year 2018, Vol 4, Issue 1

Abstract

Fundamental research on plants in order to identify their pharmaceutical agents and their effects on pathogens has been increased in medicinal plant research centers around the world, especially in Iran. This study has been conducted to determine the antibacterial effects of Pulicaria gnaphalode, Ducrosia anethifolia, Trachyspermum copticum, Foeniculul vulgare Mill, and Majorana hortensis Minch essential oils on Proteus vulgaris, Pseudomonas aeruginosa, and Shigella boydii. Their essential oils were extracted by a Clevenger apparatus following preparation of plants powder in appropriate condition. Gas chromatography-mass spectrometry (GC-MS) was used for essential oil (EOs) chemical analysis. Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were also investigated for studying the EO effects on bacteria. Sixty three compounds were identified in the EO analysis of five plants by GC-MS. All EOs tested in this study showed antibacterial properties on all three bacterial strains. EO of the Trachyspermum copticum showed stonger antibacterial effects than the other herbs. It is notable that there was a significant difference between the antibacterial activities of the EOs. The results of this study provide a scientific basis for using these plants in traditional home remedies. On the other hand, extraction and purification of these EOs can provide more phytochemicals with stronger antibiotic properties.

Authors and Affiliations

Hassan Habibi, Najmeh Ghahtan, Leila Karami

Keywords

The Hepatoprotective Role of Thiol Reductants against Mitoxantrone-Induced Liver Injury

Mitoxantrone is an anthracycline antibiotic highly effective against various human cancers. Hepatotoxicity is associated with mitoxantrone administration. On the other hand, there is no effective therapeutic option again...

Drug utilization evaluation of meropenem: an important broad-spectrum antibiotic for the treatment of serious bacterial infections in hospitalized patients

Increasing trend in the development of antibiotic resistance is one the major concerns of health care systems throughout the world. Several factors are responsible of the emergence of this problem of which frequent inapp...

EP ID EP358664
DOI -
Views 121
Downloads 0