Analysis of chylemia and its impact on blood product quality
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 7
Abstract
Objective To analyze the causes of chylemia, explore the effects of varying degrees of chylemia on subsequent blood products and the countermeasures. Methods The information of blood donors in the Central Blood Station of Xinjiang Production and Construction Corps from January 2018 to July 2022 were analyzed retrospectively, and the causes of fatty blood discarding was analyzed in terms of gender, age and times of donation. The effects of chylemia of control group, mild group, moderate group and severe group and corresponding gender and age on the hemolysis rate of suspended red blood cells(RBCs) at the end of storage and residual amount of methylene blue in the inactivated plasma were discussed. Results The incidence of chylemia in males(0.93%,84/9 047) was much higher than that in females(0.24%,9/3 781) (P<0. 05). The hemolysis rates of WBC-free suspended RBCs of mild, moderate and severe chylemia group at the end of storage(0. 19±0.08,0.28±0.06,0.66±0.25) were higher than that in control group(0.08±0.03), in males significantly higher than those in females(0.08±0.03 vs 0.06±0.02,0.21±0.09 vs 0.15±0.04,0.30±0.05 vs 0.24±0.07), in the age group of 18-30 years significantly lower than those in 31-41 years(0.07±0.02 vs 0.09±0.03) and ≥41 years(0.07±0.02 vs 0.09±0.03), P <0.05. The residual methylene blue in plasma with viral inactivation prepared from mild and moderate chylemia was significantly higher than that in control group(0.12±0.02,0.18±0.06 vs 0.06±0.02) (P<0.05). Conclusion Chylemia shall be monitored during the whole process of blood collection, and coutermeasures shall be taken to decrease the effects of chylemia on blood quality.
Authors and Affiliations
Chunyan ZHAI
Keywords
Related Articles
- EP ID EP738598
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.07.019
- Views 36
- Downloads 0
Correlation between unexpected antibody types and transfusion efficacy in patients with autoimmune hemolytic anemia (AIHA)
Objective To analyze the antibody types of autoimmune hemolytic anemia(AIHA) patients in Panyu district, Guangzhou and track the therapeutic effect of blood transfusion, so as to provide reference for clinical transfusio...
Cost-benefit analysis of hepatitis B virus serological and nucleic acid testing in blood donors
Objective In an effort to prevent transfusion-transmitted hepatitis B infection, universal HBsAg screening, HBsAg+ MP nucleic acid test(NAT) for HBV and HBsAg + individual(ID) NAT were analyzed for cost-effectiveness. Me...
Screening of hepatitis D virus in blood donors in Dalian
Objective To investigate the prevalence of hepatitis D virus in Dalian blood donors. Methods The samples reactive to HBV in blood screening were selected with the following confirmed results: 1)HBsAg+ &HBV DNA+ ; 2)HBsAg...
Distribution and molecular basis of A2 subtype in Guangzhou blood donors
Objective To investigate the distribution and molecular basis of A2 subtype among blood donors in Guangzhou. Methods Whole blood samples of 793 group A blood donors in Guangzhou Blood Center were randomly collected. A2 s...
Study on transfusion-related acute lung injury caused by HLA-Ⅱ antibody
Objective To explore the risk factors of transfusion-related acute lung injury (TRALI). Methods The clinical symptoms, signs, imaging examinations, and laboratory test results of two patients with TRALI after blood trans...