Analysis of Dinucleotide Bias and Genomic Signatures Across Cyanobacterial Genomes

Journal Title: JOURNAL OF ADVANCES IN BIOTECHNOLOGY - Year 2013, Vol 3, Issue 3

Abstract

Dinucleotide relative abundance or frequency of dinucleotides in particular nucleotide sequence is reported as genomic signature as it is specific across different DNA samples and able to identify the variance among different groups whereas identical or similar for closely related organisms. Dinucleotide relative abundance value is identified to be overall constant due to numerous factors as dinucleotide stacking energy and DNA helicity, mechanisms of replication, repair and context-dependent mutation pressures and includes information about genome-wide processes. In this study, we analyzed genome sequence of 41 cyanobacteria to gain an insight of dinucleotide bias in their genomes. Across different dinucleotides, TA is broadly underrepresented followed by CG and then AC+GT whereas; AA+TT and GC occupied a major portion of dinucleotide distribution across all cyanobacterial genomes. Underrepresentation of TA seems to be influenced by GC-content of the members as it tends to decrease when there is an increase in GC content. Members with similar GC content possess similar pattern of genomic signature. Habitats also seem to influence the dinucleotide relative abundance values of the organisms because it is suggested that marine organisms.

Authors and Affiliations

Dhananjaya P. Singh, Ratna Prabha

Keywords

Related Articles

Genetic Diversity Analysis in wild species of Pongamia pinnata (L.) using RAPD and SRAP markers.

Bio -diversityrefers to the variations within the living world while genetic diversity is the sum of genetic characteristics within any species or genus. Genetic diversity serves as a way for populations to adapt to chan...

SOME THEORETICAL AND EXPERIMENTAL FACTS CONCERNING LASER INTERACTION WITH MATERIALS OF BIOLOGICAL ORIGIN

This paper deals with characterization of materials, by the use of objective descriptions of materials optical properties. Here the materials of biological origin were tested. Authors presented their selection of the opt...

Cranberry Extract Suppressive Effect on Secretion of Inflammatory Cytokines by the Monocytic Cells

The proanthocyanidin rich fraction of cranberry (NDM) has long been speculated to possess the capacity to suppress the production of inflammatory mediators by macrophages. The objective of this investigation was to exami...

AIRLIFT BIOREACTOR FLUID-DYNAMIC CHARACTERIZATIONFOR THE CULTIVATION OF SHEAR STRESS SENSITIVEMICROORGANISMS

Airlift bioreactors are considered very efficient for aerobic cultivation of microorganisms. In particular, for the cultivation of filamentous fungi, where low shear rates may be required. In this context, the main aim o...

C-phycocyanin from Arthrospira maxima LJGR1: production, extraction and protection

C-phycocyanin (C-PC) overproduced by Arthrospira maxima LJGR1 under high urea and salt concentrations was extracted by different methods and evaluated as an antioxidant activity. A. maxima was grown in flat plate photobi...

Download PDF file
  • EP ID EP653857
  • DOI 10.24297/jbt.v3i3.5029
  • Views 91
  • Downloads 0

How To Cite

Dhananjaya P. Singh, Ratna Prabha (2013). Analysis of Dinucleotide Bias and Genomic Signatures Across Cyanobacterial Genomes. JOURNAL OF ADVANCES IN BIOTECHNOLOGY, 3(3), 265-279. https://europub.co.uk/articles/-A-653857