Analysis of epidemiological factors and biological markers of rheumatoid arthritis
Journal Title: IP International Journal of Orthopaedic Rheumatology - Year 2016, Vol 2, Issue 1
Abstract
Abstract Background: Early diagnosis is crucial in the management of rheumatoid arthritis, a prerequisite for timely intervention and to achieve better outcome. A prospective study was carried out to study epidemiological factors and biological markers of rheumatoid arthritis along with NEW ACR 2010 criteria and DAS28 aimed at early diagnosis and decreased morbidity. Material and Methods: 62 patients with various complaints indicating rheumatoid arthritis were included in this study between ages of 21 to 75 years based on new ACR 2010 criteria. Age and sex distribution, duration of disease, seasonal variation, socioeconomic status, pain in various joints, presentation with deformity and its interval from onset of disease, various biological markers (RA factor, antiCCP),disability score (das28) and VAS were observed: Results: Most common age group was 41-50 years with female-male ratio 4:1 and most commonly within 24 months of onset of disease and during winters. Most common pattern of joint involvement was wrist and MCP> PIP > Elbow, Shoulder and Knee > Ankle >Cervical >Lumbar spihe.28 joint involvement as DAS28was seen in 69.35%, 19.36% presented with classic deformity. RA factor was positive in 64.52% and Anti-CCP in 72.7% of RA factor negative cases. Mean DAS28 was 7.38 and 53.23% had NEW ACR 2010 score of 9. Conclusion: Anti-CCP can diagnose RA negative cases but if it is used together with DAS28 and NEW ACR 2010 score the accuracy of diagnosing rheumatoid arthritis improves and early treatment can be given improving its outcome and decreasing morbidity.
Authors and Affiliations
Sanjay Kumar, Ajay, Bharti, AK Gupta, AK , Gupta, Hemraj Saini
Keywords
Related Articles
- EP ID EP242860
- DOI -
- Views 97
- Downloads 0
Surgical management of proximal humerus fractures – Assessment of results
Proximal humeral fracture whether caused by trauma or related to osteoporosis, requires carefully planned individual treatment. The choice of technique and devices depends on quality of bone, soft tissue, age and reliabi...
Epidemology of glove perforation in orthopaedic surgeries
Introduction Surgical glove perforation is one of cause for percutaneous transfer of disease Among many HIV HBV HCV are deadliest diseases Among the other surgical specialities orthopaedics has the highest rate of glove...
Management of the displaced intra articular fracture calcaneum by open reduction & internal fixation with the locking calcaneum plate: A study
Introduction Since the midnineties open reduction and internal fixation is considered as the gold standard treatment for the displaced intraarticular fractures of the calcaneus by most experts However there still remains...
Use of a semi-precision attachment to fabricate a removable partial denture – a case report
Use of attachments in providing better retention to removable prosthesis is not an outdated treatment modality. It is important for dentists to have more updated knowledge about its use and the success of such prosthesis...
En-mass excision and reconstruction of GCT in 1st metatarsal in incidentally diagnosed young diabetic: A case report
Giant Cell Tumour (GCT) which is a locally aggressive benign bone tumour with malignant potential rarely occurs in metatarsal. We present a case of GCT of first metatarsal bone in a 26 year old male with incidentally dia...