Analysis of factors affecting long-term survival in surgically-treated second primary lung cancer patients with previous malignancy
Journal Title: Ege Tıp Dergisi - Year 2015, Vol 54, Issue 4
Abstract
Aim: Multiple cancer rates increase with an average increased lifespan. Therefore, many malignant patients are at high risk for a second primary malignancy. This study aims to evaluate lung cancer patients with a previous malignancy. Materials and Methods: Forty-five patients who underwent resection for a second primary lung cancer in our department between January 2007 and June 2013 were reviewed retrospectively. Results: The patients included 37 (82.2%) males and eight (17.8%) females. When the patients were evaluated for the first primary malignancy, the distribution of the malignancies according to the systems was 14 (31.1%) urogenital malignancies, ten (22.2%) respiratory, six (13.3%) hematological, six (13.3%) endocrine, five (11.1%) malignancies, and four (8.9%) integumentary malignancies. The comparison of the site of primary malignancy and survival data showed that the rates of long-term survival were shorter in patients with gastrointestinal system malignancies and the difference was statistically significant (p=0.028). The long-term survival of patients who received chemotherapy after the resection of the first primary lung cancer was significantly shorter (p=0.016). Conclusion: The follow-up of patients should be done more carefully by the consideration of the positive effects of early diagnosis on cancer prognosis and keeping in mind the risk of primary lung cancer development in a patient with other system malignancy. We especially recommend caution in administering chemotherapy to patients with double primary tumors after a lung cancer operation.
Authors and Affiliations
Ayşe Gül Ergönül, Ali Özdil, Tevfik İlker Akçam, Kutsal Turhan, Alpaslan Çakan, Ufuk Çağırıcı
Keywords
Related Articles
- EP ID EP344567
- DOI 10.19161/etd.344157
- Views 115
- Downloads 0
Primer biliyer sirozda çölyak hastalığı birlikteliği
Amaç: Otoimmun hastalıklar genel olarak birliktelik gösterme eğilimindedirler. Primer biliyer siroza (PBS) da diğer otoimmun hastalıkların yanı sıra çölyak hastalığı (ÇH) eşlik edebilmektedir. Bu çalışmada PBS’li hastala...
Kanser immünoterapisi sırasında gelişen inflamatuvar artrit olgusu
Günümüzde modern tıpta yaşanan teknolojik ve bilimsel gelişmeler solid ve hematolojik malignitelerin tedavisinde yeni tedavi stratejilerin ortaya çıkmasını sağlamıştır. Bu gelişmelerden biri de kanser immünoterapisi olar...
Delirium and tremor associated with ertapenem treatment
Though seizures are the most commonly reported neurotoxic adverse effects of ertapenem, there are numerous other side effects including hallucinations, disorientation, and tremors which are hardly ever reported. These si...
Adrenal insufficiency in a 19-year-old male patient admitted with fatigue
Adrenal insufficiency is quite rare and 70-90% of cases develop as a result of autoimmune adrenalitis. The rest may be the result of infections, metastasis, adrenal haemorrhage / infarct or adverse effects of drugs. Prim...
Efficacy of intravenous midazolam in dental implant surgery
Aim: The long-lasting procedure in dental implant surgery may impair a patient’s tolerance and make the working conditions for the surgeon difficult. The aim of this study was to explore the effect of administering consc...