Analysis of Lymphocytes Count in Premenopausal Women with Iron Deficiency Anemia
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 10
Abstract
Background: Iron deficiency is one of the most common known forms of nutritional deficiency in the world. Iron-deficiency anaemia (IDA), which occurs due to nutritional deficiency, is a major health problem in developed and developing countries. Aim of the study: To analyze lymphocytes count in premenopausal women with iron deficiency anemia. Materials and methods: The study was conducted in the Department of General Pathology of the medical institution. The approval of the study protocol was obtained from the ethical committee of the institute. For the study, we selected 80 pre-menopausal women between the age group of 18-40 years who were diagnosed with iron deficiency anemia and their hemoglobin level was less than 10 g/dL. 80 pre-menopausal women with normal hemoglobin level were recruited after matching with the subjects for control group. Results: The mean age of the patients in study group was 30.25 years and in control group was 31.11 years. There were 80 subjects in each group. Table 2 shows the mean lymphocyte count in peripheral venous blood in pre-menopausal women with Iron deficiency anemia and normal healthy women. The mean CD3+, CD4+, CD8+, and CD19+ lymphocyte counts were 1.77, 0.88, 0.69, 0.42, 1.81 X 109/L, respectively, in study group, and 1.93, 0.52, 0.85, 0.34 and 1.90 X 109/L, respectively, for the control group. The absolute T lymphocytes (CD3+) and subpopulations (CD4+, CD8+) in the iron-deficient group were significantly lower than in the control group. Conclusion: Within the limitations of the study, this can be concluded that significant change in seen in the lymphocyte count in premenopausal women with iron deficiency anemia.
Authors and Affiliations
Dushyant Sharma, Pallavi Sharma
Keywords
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