Analysis of Microbial Profiles and Their Resistance Pattern in Pleural Fluid Samples from a Tertiary Care Centre.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Background: Acute respiratory tract infection is the leading cause of morbidity and mortality. Several possible mechanisms of pleural effusion have been proposed accompanying various underlying diseases like Heart failure, Pneumonia, Pleural malignancy & Cirrhosis Liver. One of the major problems world-wide is the increase in antibiotic resistant strains of bacteria, which has proved difficult to control. Objectives: To identify the presence of lactose fermenting bacilli in pleural fluid samples with their resistance pattern along with different enzyme mechanisms responsible for resistance. Material and methods: This study was carried out in Microbiology Division of Central laboratory, SMIH, Patel nagar, Dehradun. A total number of 215 samples, over a period of 12 months from November 2016 to October 2017, were collected for the examination. Out of which, only 31 positive samples were processed to determine the etiology and antimicrobial susceptibility pattern using VITEK 2 compact system. All patients suffering from tuberculosis were excluded from the study. Results: Out of total samples, only 31 samples showed culture positivity with majority of Gram negative bacilli (23). Among Gram negative bacilli, 12 were lactose fermenters. Enterobacter spp (07/12) was the predominant isolate with high resistance for Piperacillin Tazobactum which is now the only drug left for treatment in most of the cases. Conclusion: The study was carried to find out the microbiological association of pleural effusion in nontubercular cases. Indiscriminate and overuse of broad spectrum antibiotics predisposes the affected patients to develop multi drug resistant virulent micro flora.
Authors and Affiliations
Khan Z. I. , Jauhari S. , Kataria V. K
Keywords
Related Articles
- EP ID EP467050
- DOI 10.9790/0853-1802063540.
- Views 81
- Downloads 0
Pheochromocytoma: A Rare Cause of Hypertension
I hereby report a case of pheochromocytoma, rare cause for hypertension. Pheochromocytomas are rare tumours arising from adrenal medulla and it can present with abdominal pain and headache . A 35 year old lady with no co...
Clinico-Histopathological Study of Cervical Carcinoma At A Tertiary Care Hospital.
Aims And Objective:To study various types of cervical carcinoma and correlate histopathological findings with the clinical presentation of the patient. Material And Methods:The present study is a prospective study done o...
Burkitt”S Lymphoma of Small Bowel – A Case Report
A 15 year old boy was admitted with a history of lower abdomen pain and vomiting for 2 months. On evaluation ct pictures were suggestive of small bowel lymphoma. He underwent laparotomy and found to have tumor arising fr...
A cross sectional study to evaluate the carrying angle in a tertiary care set up in eastern India.
The carrying angle of the elbow is defined as the angle formed by the long axis of the arm and the long axis of the forearm in the frontal plane when the elbow is fully extended and the forearm is supinated forearm. This...
Splenic Cystic Lymphangioma, A Rare Cause Of Massive Splenomegaly In Adults: A Case Report and review of Literature.
Introduction: Lymphangioma of the spleen is a very rare entity in adults, we therefore deemed it necessary to share this finding with colleagues and highlight the diagnostic challenges inherent in arriving at a preoperat...