Analysis of Papulosquamous Skin Disorders in Skin Biopsies: A Clinico Histopathological Study
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 4
Abstract
Background: Papulosquamous disorders assume considerable importance because of their frequency of occurrence. As all the lesions are characterized by scaling papules and plaques, clinical confusion may occur in their diagnosis and hence these lesions are commonly misdiagnosed. Separation of each of these lesions becomes important because, for each disease, the treatment and prognosis is disease specific. Aim: To analyse various papulosquamous disorders of skin, to study the histopathological features and also to know the correlation between clinical and histopathological diagnosis. Materials and Methods: This study was done in the Department of Pathology, Narayana medical college and hospital, Nellore, Andhrapradesh, India for a period of 1 year from June 2016 to June 2017. Total 108 cases of papulosquamous skin disorders were studied. Results: Psoriasis was the commonest lesion (53.70%), followed by Lichen planus (29.63%), Pityriasis rubra pilaris (7.41%), Lichen nitidus (5.55%) and Parapsoriasis (3.70%). Papulosquamous skin lesions were common in 2140years age group (38.9%). Papulosquamous skin lesions were more common in males, than females with a male:female ratio of 1.7:1. Both age and sex distribution of cases showed significant p value < 0.001. In our study, histopathology confirmed the clinical diagnosis in 42.6% of cases. Histopathology gave the diagnosis when differential diagnosis were there in 51.85% of cases and in 5.55% of cases, histopathological diagnosis was different from clinical diagnosis. Conclusion: Our study concludes that histopathology is the gold standard investigation for diagnosis, categorization and clinicopathological correlation of papulosquamous skin disorders.
Authors and Affiliations
Muram Reddy Vijaya Lakshmi
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