Analysis of pattern of change of VAS and WOMAC between autologous bone marrow derived mesenchymal stem cells enhanced with platelet rich plasma versus platelet rich plasma in osteoarthritis knee
Journal Title: International Journal of Orthopaedics Sciences - Year 2017, Vol 3, Issue 1
Abstract
Introduction: Osteoarthritis (OA) is a chronic degenerative disorder that is characterized by a loss of articular cartilage, in the synovial joints which is characterized by sclerosis subchondral bone thickening, marginal osteochondral outgrowths (osteophytes). Several risk factors have been identified, such as obesity, occupation, higher age, biomechanics and increased dynamic loading of the joint and joint injury, and invoves the weight bearing joints like hip and knee joint Methodology: The sample size studied was 32 patients of which 16 patients in each group.The patients were selected after going through the inclusion and exclusion criteria. The patients were examined clinically regarding VAS score KOOS score and WOMAC score recorded each patient was investigated by routine blood tests investigation X ray, MRI Results: The group 1 had baseline pain score of mean 9.38 with (SD±2.187) and in group 2 had baseline pain score of mean 9.13 (SD±1.586). Both groups were comparable and were statistically significant with p value of 0.571. At final follow up, WOMAC score of group 1 had mean 1.25 (SD±0.557) and group 2 had mean of 1.00 (SD±0.00), It was not significant (p= 0.74). Conclusion: A trend towards gradual and progressive decline of the VAS is noted in the patients over the period of three follow ups from the baseline score
Authors and Affiliations
Dr. Sunil Kumar TR, Dr. Harish YS
Keywords
Related Articles
- EP ID EP501397
- DOI 10.22271/ortho.2017.v3.i1j.97
- Views 105
- Downloads 0
A prospective study of functional outcome in intra articular distal humerus fracture treated with dual plating
Background: In adults, distal humerus fractures are uncommon and intra-articular, oftenly involve both the medial and lateral columns. Open reduction and surgical fixation with plating gives good results. The aim of this...
Analysis of percutaneous tension band wiring for patellar fractures
Aim: Patella fractures are more common and account for approximately 1% of all fractures1. The most common method of fixation is a modified tension band wiring by using 2 k wires through a midline longitudinal incision w...
Avascular necrosis of the femoral head due to sickle-cell disease in tribal population around Vishakhapatnam district, treated with core de-compression and non - vascularised fibular graft
Sickle-cell disease (SCD) is the most common cause of avascular necrosis (AVN) of the hip in childhood. It results in significant physical impairment and chronic pain, and ohen progresses to require hip replacement. Cons...
Prevalence of lumbar disc herniation and disc degeneration in asymptomatic Indian subjects: An MRI based study
Background: India is a country with a huge human resource been utilised for labour and also is a country of diversity in culture and religions. Thus we have numerous activities which involve bending and twisting of the s...
Functional outcome of high tibial osteotomy among patients with osteoarthritis
Introduction: Osteoarthritis of knee is more common among all types of arthritic conditions. High tibial osteotomy is an accepted surgical technique for treatment of medial compartment arthrosis of knee in younger patien...