Analysis of Red Cell Profile: Red Cell Distribution Width, Hemoglobin, Mean Corpuscular Volume in Elderly Patients
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 3
Abstract
Introduction: Red cell distribution width (RDW), a numeric measure of variability in the size of circulating erythrocytes is a routinely reported haematological parameter commonly part of complete blood cell count. RDW was found to be a strong independent predictor of poor outcome in a variety of cardiovascular disease states even after adjustment for potential confounders, including anaemia and renal dysfunction. The present study was undertaken to analyze the variation in RDW, Hb% and MCV in elderly patients with various illnesses. Aim and Objective: 1. To study the pattern of Red cell Distribution width (RDW) in elderly patients in different diseases. 2. To correlate increased RDW values with other RBC parameters like Hb% and MCV. Materials and Methods: Material for the study consisted of RBC parameters like Hb%, MCV of consecutive patients aged more than 65 years, who had increased RDW, irrespective of their sex and illness which were retrieved from laboratory records. These patients (both in patients and out patients) were referred to haematology laboratory whose Ethylene Diamine Tetra Acetic acid (EDTA) blood samples were analyzed by automated hematology analyser (Horiba Abxpentraxl 80.303pxl 5748 analyzer). Relevant clinical data of these patients like age, sex and clinical diagnoses were also obtained from the clinical records. Data analyzed was expressed in numerals and percentage. Results: Out of 196 patients, blood samples of 60(30.16%) patients had increased RDW, out of which 39(65%) were males and 21(35%) were females. IHD formed the major portion of patients with increased RDW comprising of 31(51.66%) patients. 36 patients had Hb<10gm %( 59.9%) and 40 (66.6%) patients had MCV <70fL. Conclusion: Most of the patients with increased RDW were those with IHD. Majority of them were males. The biologic mechanisms underlying the association of RDW with various diseases merit investigation. RDW is an inexpensive test routinely reported to physicians, further research is needed to determine whether RDW is an useful risk assessment tool in different clinical settings apart from the ones which are proved.
Authors and Affiliations
Laxmi Ronada
Keywords
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- EP ID EP466489
- DOI 10.21088/ijprp.2278.148X.6317.18
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