Analysis of retinal nerve fiber layer thickness in cognitive impairment
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 2
Abstract
Introduction Cognitive impairment may be present at birth or can occur later in adulthood Few studies have shown correlation of cognition with retinal nerve fiber layer thickness RNFL The present study was planned to analyse RNFL thickness in disorders of cognitionMaterials and Methods 60 eyes of cognitive impairment were included All patients underwent RNFL thickness measurement by OCT at initial visit and after 3 months Statistical analysis was done with a p value less than 005 to be significantResults 60 eyes of cases of cognitive impairment were included 16 53 cases had cognitive impairment following traumatic brain injury and 14 47 cases were secondary to Alzheimers disease The mean RNFL thickness in the superior quadrant was 10592 m 28343m at initial visit and at 3 months follow up was 10572 m27916 m in the nasal quadrant was 6917 m 13199m at initial visit and at 3 months follow up was 6897 m 13119 m in the inferior quadrant RNFL thickness was 11103 m22558 mat initial visit and at 3 months follow up was 11092 m22372 m in the temporal quadrant was 5935 m 11333 m at initial visit and at 3 months follow up was 5918 m 11247 m but the difference was not statistically significant Subgroup analysis of cases also did not show any statistically significant difference in RNFL thicknessConclusion RNFL thickness remains unaffected in cognitive disorders However studies on a large sample of patients with a longer follow up are neededKeywords Cognitive impairment RNFL thickness Optical coherence tomography
Authors and Affiliations
Praveen Kumar K V, Sharad Nivrutti Gomase, Chiranjeevi P
Keywords
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- EP ID EP474199
- DOI 10.18231/2395-1451.2018.0041
- Views 73
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