Analysis on the neurological mechanism of acupuncture treatment in Idiopathic tinnitus based on the theory of “central plasticity”

Journal Title: TMR Integrative Medicine - Year 2021, Vol 5, Issue 32

Abstract

Recent studies have found that although tinnitus originates from the cochlea, its root lies in the plasticity of the auditory center. In other words, the peripheral auditory system damage causes abnormal excitement and even functional reorganization of the brain stem and cerebral cortex, finally leading to tinnitus progresses and persists in the center. The mechanism of "central plasticity" is related to the physiological characteristics of related brain regions, the characteristics of electrophysiological changes, the changes of central neurotransmitters, and psychological factors. It is speculated that the possible mechanisms of the acupuncture treatment of tinnitus are as follows: 1. Acupuncture can alter the level of neurotransmitters 5-HT and GABA in nerve center, that is, GABA increases and 5-HT decreases after acupuncture; 2. Acupuncture changes the wrong central pattern of the cerebral cortex caused by tinnitus through strong stimulation, and aids the cerebral cortex adapt to the changes of the internal and external environment to produce benign functional reorganization, in order to treat tinnitus; 3. External stimulation of acupuncture can accelerate the contraction of muscle vessels around the ears, accelerate blood circulation and metabolism, and improve the blood supply of the auditory system, thus improving tinnitus. 4. Acupuncture can improve or even cure tinnitus by stimulating the acupoint-nerve pathway around the ear, regulating unbalanced neurotransmitters, inhibiting abnormal nerve discharge, correcting wrong auditory pathway patterns, and establishing new auditory pathway nerve conduction patterns.

Authors and Affiliations

Peng-Xi Zhang, Tong-Sheng Su

Keywords

Related Articles

Potential Mechanism of Huangqi Guizhi Wuwu Decoction for Cervical Spondylosis treatment based on Network Pharmacology

Objective: To study the potential mechanism of Huangqi Guizhi Wuwu Decoction in the treatment of cervical spondylosis based on the network pharmacological method, and to provide a basis for clinical application and pharm...

Meta-analysis of efficacy and safety of Qianliexin capsule combined with western medicine in benign prostatic hyperplasia treatmen

Objective: To systematically evaluate the efficacy and safety of Qianliexin capsule combined with western medicine in benign prostatic hyperplasia treatment. Methods: Randomized controlled trials of Qianliexin capsule co...

The prognosis and survival of integrated traditional Chinese and Western medicine on glioma: a meta-analysis

Objective: To systematically access the effects of integrated traditional Chinese and western medicine treatment versus western medicine treatment alone in glioma. Methods: Published randomized controlled trials were inc...

Bioinformatic analysis reveals novel biomarkers and candidate drug compositions in prostate cancer

As prostate cancer (PC) patients do more and more genome sequencing, we can predict prognosis through individual oncogenic mutations. Although great success have been made to clarify the incidence of PC, the mechanisms...

Effects of Yishenbupi (tonifying-kidney and invigorating-spleen) prescription on the expression of renal fibrosis-associated proteins in unilateral ureteral occlusion rats

Objective: To evaluate the effects and mechanism of the Yishenbupi (tonifying-kidney and invigorating-spleen) prescription on the expression of renal fibrosis-associated vimentin, α-SMA, and fibronectin in unilateral ure...

Download PDF file
  • EP ID EP701892
  • DOI 10.53388/TMRIM202105032
  • Views 50
  • Downloads 0

How To Cite

Peng-Xi Zhang, Tong-Sheng Su (2021). Analysis on the neurological mechanism of acupuncture treatment in Idiopathic tinnitus based on the theory of “central plasticity”. TMR Integrative Medicine, 5(32), -. https://europub.co.uk/articles/-A-701892