Ancestry Informative Markers: Getting a Lot Out of a Little
Journal Title: International Journal of Current Microbiology and Applied Sciences (IJCMAS) - Year 2018, Vol 7, Issue 10
Abstract
The SNP markers have emerged as essential resources for performing genetic linkage, association, and admixture studies. Both academic and commercial groups are developing large numbers of genome-wide SNP datasets. These databases are utilised for several studies involving both structural and functional genomics. Some studies viz. admixture mapping, population structure identification and quantifying genetic diversity requires a genome-wide small informative panel of relatively evenly spaced markers. These informative markers can distinguish the ancestral origins of chromosomal segments in admixed individuals and can delineate the ancestral origin of a particular population. Thus present study reviews existing methods to select ancestry informative markers and their comparative efficiency in inferring individual ancestry level.
Authors and Affiliations
Supriya Chhotaray, Aamir Bashir Wara, Dhan Pal, V. Bhanuprakash, Harshit Kumar, Snehasmita Panda, Mitek Tarang, Subhashree Parida, Bharat Bhushan, Manjit Panigrahi
Keywords
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- EP ID EP582806
- DOI 10.20546/ijcmas.2018.710.012
- Views 64
- Downloads 0
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