Anemia in Patients with Type 2 Diabetes in Absence of Renal Impairment
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 8
Abstract
Objectives: this study aims to determine the prevalence of anemia in patients with type 2 diabetes in absence of renal impairment and its association with microalbuminuria and estimated glomerular filtration rate (eGFR). Materials and Methods: this study included 100 patients with type 2 diabetes without renal impairment (eGFR ≥ 90ml/min) and 35 healthy subjects as control group. For all studied subjects, full history, physical examination and the following laboratory investigations were done: complete blood count, fasting and postprandial serum glucose, hemoglobin A1c, serum creatinine, eGFR, spot urine analysis for microalbuminuria. Results: the study showed that anemia was present in 34% of patients with type 2DM in absence of renal impairment. The anemic diabetic group had a significantly longer duration of diabetes, significantly lower eGFR and significantly higher urinary albumin excretion rate than the non-anemic diabetic group with Pvalue=0.000 for each. In the diabetic patients, the study showed that the hemoglobin level had highly significant negative correlation with the duration of diabetes (r=-0.370, P=0.000) and the urinary albumin excretion rate (r=-0. 508, P=0. 000), while it had highly significant positive correlation with eGFR (r=0. 359, P=0. 000). Conclusions: we concluded that the prevalence of anemia in patients with type 2 diabetes in absence of renal impairment was 34%. The diagnosis of anemia in diabetic patients may be good indicator for early diagnosis of kidney injury and diabetic nephropathy, therefore hemoglobin level can be used as a simple tool for diabetic patients’ follow up
Authors and Affiliations
Dr Salah A Argoon
Keywords
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