ANTHELMINTIC AND ANTIMICROBIAL PROPERTIES OF LEAVES OF BRUGUIERA GYMNORRHIZA (L.) LAM
Journal Title: Int J of Pharm Rev& Res - Year 2011, Vol 1, Issue 1
Abstract
The objective of the present investigation was to determine the anthelmintic and antimicrobial activity of petroleum ether extract of the leaves of Bruguiera gymnorrhiza (L.) Lam. Anthelmintic activity of this extract was evaluated on Indian adult earthworms, Pheretima posthuma, and exhibited a dose dependent inhibition of spontaneous motility (paralysis), and evoked responses to pin-prick, and the effects were comparable with that of piperazine citrate. The extract were also assayed for antimicrobial activity against various Gram positive organisms such as Staphylococcus epidermidis, Micrococcus luteus, Bacillus subtilis, and Gram negative organisms such as Escherichia coli, Pseudomonas vulgaris, Salmonella typhi, and fungal strains Aspergillus niger, and Candida albicans. Antimicrobial activity was conducted by the agar well diffusion method. The extract showed varies levels of antimicrobial activity on different test microorganisms. Future studies are in process to isolate the active principles responsible for the activity.
Authors and Affiliations
K. R. Vandana , K. Bhagya Deepthi , K. Yugandhar , P. S. Kiran , A. Saravanakumar
Keywords
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