Anthracycline Cardiotoxicity: Strategies for Prevention and Intervention
Journal Title: Heart Research – Open Journal - Year 2015, Vol 2, Issue 4
Abstract
The cardiotoxic effects of anthracycline compounds, used extensively to treat malignancies such as breast cancer and lymphoma, are well known.1,2 However, despite efforts towards cardioprotective strategies and early detection of anthracycline cardiotoxicity, defined as decline in Left Ventricular Ejection Fraction (LVEF) of ≥10% from baseline or to <50%,3,4 there is currently no consensus on the optimal approach. Current clinical practice guidelines recommend serial LVEF monitoring to identify cardiotoxicity in high-risk patients receiving anthracyclines;
Authors and Affiliations
Guilherme H. Oliveira
Keywords
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- EP ID EP556923
- DOI 10.17140/HROJ-2-e004
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