Anti-Anemic Activity of Ethanolic Leaf Extract of Kedrostis foetidissima in Phenylhydrazine Induced Anemic Rats
Journal Title: Scholars Academic Journal of Biosciences - Year 2016, Vol 4, Issue 8
Abstract
The aim of the present study is to evaluate the anti-anemic activity of ethanolic leaf extract of Kedrostis foetidissima against phenylhydrazine induced hemolytic anemia in rats. Phenylhydrazine (60mg/kg) was administered intraperitoneally for 2 days to induce anemia in rats. The animals were divided in to four groups of 6 animals each. Group I served as normal control, group II as anemic control, group III as reference control administered with Vitamin B12 and group IV animals were treated with 200mg/kg, of ethanolic leaf extract of Kedrostis foetidissima. All the test drugs were administered once daily for 28 days through oral route. On 29th day blood was withdrawn, through sinus puncture under phenobarbitone anesthesia and subjected to the estimation of RBC, Hb and percentage Hematocrit. Both the ethanolic leaf extract of Kedrostis foetidissima and Vitamin B12 significantly increased the RBC, Hb and Hematocrit levels which conclude that, Kedrostis foetidissima leaf extract exhibits anti-anemic activity. Keywords: Anemia, Anti-anemic activity, Kedrostis foetidissima and Vitamin B12.
Authors and Affiliations
Baskaran K, Suruthi B
Keywords
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