ANTI-ANEMIC ACTIVITY OF SPROUTS OF VIGNA RADIATA L. IN MALE ALBINO RATS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 11
Abstract
Objective: To evaluate the anti-anemic activity of sprouts of Vigna radiata L. against phenyl hydrazine induced anemic rats.Methods: Rats were divided into 4 groups of 6 each. Group 1 was given normal saline and served as control and all other groups were given 40 mg/kg b. w of phenyl hydrazine for 2 d to induce anemia. Group 3 was treated with Bioferon (230 mg/kg) and served as the standard. Group 4 was treated with sprouted Vigna radiata L. (600 mg/kg bw). All the treatments were given orally. On completion of the experimental period, all the test substance/vehicle-treated rats were sacrificed and the plasma separated was used for estimating various biochemical as well as hematological parameters as per standard procedures. Results: The experimental rats treated with sprouted Vigna radiata L. at the dose level 600 mg/kg bw for 13 d revealed significant changes in biochemical and hematological parameters compared to phenyl hydrazine induced anemic rats.Conclusion: The present study concluded that the sprouted Vigna radiata L. inhibits anemia induced by phenyl hydrazine in male albino rats. Â
Authors and Affiliations
Manikandaselvi S. , David Raj C. , Aravind S. , Ravikumar R. , Thinagarbabu R. , Nandhini S.
Keywords
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