ANTI ARTHRITIC ACTIVITY OF CAESALPINIA PULCHERRIMA AGAINST TYPE II COLLAGEN INDUCED ARTHRITIS IN EXPERIMENTAL RATS
Journal Title: International Journal of Pharmaceutical Sciences and Drug Research - Year 2015, Vol 7, Issue 2
Abstract
Caesalpinia pulcherrima is a medicinal plant belonging to the family Caesalpiniaceae. The main aim of the present study was to investigate the Anti Arthritic activity of the ethanolic extract of Caesalpinia pulcherrima (ECP) at the dose of 200 mg/kg and 400 mg/kg on Type II Collagen induced Arthritis in experimental rats. In collagen induced arthritic rats, there was significant enhance in rat paw volume and reduce in body weight, whereas ECP and Aspirin treated groups showed significant decrease in paw volume and normal gain in body weight. The altered hematological parameters (Hb, RBC, WBC, ESR and CRP) in the arthritic rats were significantly recover to normal by administration of ECP. Further the radiological studies revealed the anti arthritic activity of ECP by indicating less abnormality in extract treated groups when compared to the arthritic control group. Findings from the present investigations suggest that the ethonolic extract of Caesalpinia pulcherrima exhibits significant anti arthritic activity.
Authors and Affiliations
C Rajaram, K Ravindra Reddy, K B Chandra Sekhar
Keywords
Related Articles
- EP ID EP625064
- DOI -
- Views 70
- Downloads 0
ANTI ARTHRITIC ACTIVITY OF CAESALPINIA PULCHERRIMA AGAINST TYPE II COLLAGEN INDUCED ARTHRITIS IN EXPERIMENTAL RATS
Caesalpinia pulcherrima is a medicinal plant belonging to the family Caesalpiniaceae. The main aim of the present study was to investigate the Anti Arthritic activity of the ethanolic extract of Caesalpinia pulcherrima (...
PHYTOCHEMICAL SCREENING AND APHRODISIAC ACTIVITY OF ASPARAGUS RACEMOSUS
The plant Asparagus racemosus is widely distributed in the Himalayan and sub-Himalayan regions of India. Based on preliminary reports, there is a lot of interest in using the roots of this plant for treating sexual disor...
FORMULATION AND EVALUATION OF A MOISTURIZING CREAM USING ALMOND BUTTER
Almond butter is one of the moisturizing agents, which has good emollient and moisturizing properties and hence can be well utilized to design a moisturizing cream, which can provide a good moisturizing property and help...
NEW STABILITY-INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF ROSUVASTATIN (CALCIUM) IN PHARMACEUTICAL DOSAGE FORMS
A stability indicating, accurate, specific, linear and sensitive reverse phase-HPLC method was developed and validated for the determination of Rosuvastatin calcium (ROS) in pharmaceutical dosage form. The chromatographi...
BENZOTHIAZOLE: DIFFERENT METHODS OF SYNTHESIS AND DIVERSE BIOLOGICAL ACTIVITIES
Substituted 1, 3-benzothiazole derivatives are an important class of heterocyclic compounds. In recent years heterocyclic compounds analogues and derivatives have attracted strong interest due to their biological and pha...