ANTI-ARTHRITIC EVALUATION OF SOME TRADITIONALLY USED MEDICINAL PLANTS IN FCA INDUCED ARTHRITIS IN RATS
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2017, Vol 7, Issue 5
Abstract
Aim of Study: The main of study is to evaluate the anti-arthritic activity of some Traditionally Used Medicinal Plants in FCA Induced Arthritis in Rats. Material & Methods: All the selected medicinal plants were extracted by using methanol using soxhlet apparatus. Arthritis was induced by FCA in rats and body weight; hematological parameters were measured at the end of experiment. Results: The assessment made on the 21st day showed that the N. arbor-tristis and A. scholaris treatments at both doses (low and high) had moderately significant and highly significant effect and reduced (p< 0.01& p<0.001). N. arbor-tristis, A. scholaris had highly significant effects (p<0.001) in recovery of RBCs and haemoglobin. They also showed highly significant effects on decrease in WBCs and ESR. B. monosperma and B. diffusa extract treated groups, also showed moderately significant effects as compared to arthritic group. Conclusion: By comparing the results of the selected plants in FCA induced arthritis, it could be concluded that methanolic extracts of Nyctanthes arbor-tristis, Alstonia scholaris and Butea monosperma have most potent and highly significant anti-arthritic activity.
Authors and Affiliations
Om Prakash Tiwari
Keywords
Related Articles
- EP ID EP296182
- DOI 10.22270/jddt.v7i5.1475
- Views 103
- Downloads 0
MANAGEMENT OF GLAUCOMA: EFFECTIVE DRUG DELIVERY VIA NIOSOMES
Glaucoma is a term used for a group of diseases; associated with optic nerve damage which leads to loss of retinal ganglionic cells. The changes stimulated in the optic nerve head cause visual field restriction which may...
A ROLE OF MACROPHAGES: AN OVERVIEW
The macrophage is a type of phagocytic cell, which is a type of cell those are responsible for detecting, engulfing and destroying pathogens and apoptotic cells. Macrophages are produced through the differentiation of mo...
MODULATING MULTIPLE DRUG RESISTANCE VIA CO-DELIVERY OF NANOPARTICLE
When various mechanisms in cancer causing cells show resistance towards one or many chemotherapeutics, it hinders the efficacy of chemotherapy. This is referred as multidrug resistance. There are several factors that con...
A REVIEW ON FAST DISSOLVING TABLET
The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery inspite of various disadvantages. Fast disinte...
Ayurveda Kayachikitsa towards the management of joint pain: a review
Joint pain is one of the very common problems amongst the elderly age population. Clinically it is characterized by shula, shotha and prasaarana-aakunchanayo pravruttischa vedana. Ayurveda described various treatment mod...