Anti Bacterial and Anti Oxidant Activities of Evolvulus Alsinoides Linn
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 1
Abstract
Plants are very important sources of potential useful raw materials as natural chemotherapeutic agents. Shankhpushpi is botanically termed as Evolvulus alsinoides; the extracts have exhibited antioxidant, anti-ulcer, and immunomodulatory activities. The present work is to investigate the invitro therapeutic potential activities of methanolic extract of whole plant of Evolvulus alsinoides on the antimicrobial activity against five clinical pathogenic bacterial strains viz., Staphylococcus aureus, Bacillus cereus, Escherichia coli, Klebshiella pneumonia and Salmonella typhii, using agar well diffusion assay and Anti oxidant activity using 1-1-Diphenyl2-picryl-hydrazyl (DPPH) radical. Extract inhibited IC50: 40.2. Total phenolic content: 28.4 mg/ml & Total flavonoid content: 20.2 μg /ml. Evolvulus alsinoides (MIC): 512.5mg/ml possess 30 to 40 % inhibition, the antibacterial activity of the herbal extracts was more pronounced on the gram- negative bacteria Klebshiella pneumonia than the gram-positive bacteria Staphylococcus aureus. The free radical scavenging activity of methanolic activity of whole plant of Evolvulus alsinoides increase in a concentration dependent manner, and posses statistically significance DPPH free radical scavenging & Anti microbial activities
Authors and Affiliations
Nazanin Soudbakhsh Moghadam1, Anil Kumar H. V, Laksmikanth. R. N3 ,, Muralidhar. S. Talkad4, Meghna Nagaraj5, Manasa D. R
Keywords
Related Articles
- EP ID EP388237
- DOI 10.9790/3008-1201038386
- Views 69
- Downloads 0
Ethnobotanical Survey Of Medicinal Plants Used For Treatment Of Malaria By Kipsigis People In Kericho County, Kenya.
Ethnobotanical pharmacopoeia is importantly used in intervention of disease and need arises for documentation and preservation of tradition medicinal knowledge to boost the discovery of new drugs. Due to the emergence of...
Evaluation of Plasma Creatine Kinase Activity and Inorganic Phosphate among Sudanese Patients with Sickle Cell Disease in Khartoum and White Nile State
Background: CK and phosphorus are helpful biomarker for detection of early renal abnormality particularly CK which has been shown to be abetter predicator of acute renal failure. Objectives: This is a descriptive cross-s...
Squamous cell carcinomas arising in seborrheic keratosis of external auditory canal: unusual situation
We report an unusual case of seborrheic keratosis (SK) of theright external auditory canal in 78- year-old female patient, revealed by right malignant otitis externa andcaused impaired hearing, by obstructing the externa...
Phytochemical and Antimicrobial Screening of Cocculus hirsutus L.
Many number of the plant species including Cocculus hirsutus L. is being used as the sources of herbal medicine. Present work was mainly focused with the identification of the therapeutic properties of Cocculus hirsutus...
Occurrence Of Nematodes And Trematode Cercariae In Lymnea Species Of Danmadahun Part Of Jakara Dam, Kano State, Nigeria
This paper reports the occurrence of nematodes and trematode cercariae in Lymnea species of one part of Danmadahun in Jakara dam, Kano state, Nigeria. This study was initially carried out between October to January 2017...