Anti-Diabetic potential of herbal remedies on the glucose transport gene (GLUT) in liver and skeletal muscles
Journal Title: Journal of Research in Biology - Year 2015, Vol 5, Issue 8
Abstract
For a long time, several herbal medicines have been used for the treatment of diabetes in the form of compound drugs. Moreover, after the references made by researchers on diabetes mellitus, investigations on the hypoglycemic activity of compound drugs from medicinal plants have been more important. Although, the molecular mechanisms behind this effect is not much explored yet. There are various approaches to reduce the diabetes effect and its secondary complications, and herbal drugs are more preferred due to its less side effects and low cost. One of the major factors in the development of diabetes and its complications is the damage induced by free radicals. Therefore antidiabetic compounds with antioxidant properties would be more beneficial. It is hypothesized that the insulin mimetic effect, hypoglycemic effect and β-cell function of herbal remedies might add to glucose uptake through improvement in the expression of genes of the glucose transporter (GLUT) family in liver and skeletal muscles. Here we selected some plants with the ability to control blood glucose as well as to modulate some of the mechanisms involved in insulin resistance like β-cell function, glucose transport (GLUT) gene and incretin related pathways. Therefore, plants remedies may be appealing as an alternative and adjunctive treatment for diabetes mellitus
Authors and Affiliations
Waleed M. Al-Shaqha
Keywords
Related Articles
- EP ID EP567659
- DOI -
- Views 78
- Downloads 0
Genetic analysis of F2 population of tomato for studying quantitative traits in the cross between Bushbeef x Nagina
This study aims to determine the genetic components like Vg(Variance of genotype), Vp ( Variance of phenotype), GCV (Genotypic co-efficient of variation), PCV (Phenotypic coefficient of variation), Hb (Heritability) and...
Ethno-Veterinary Practices for Cattle Diseases in Ganjam District of Orissa, India
The present communication reports on few time-tested practices of 36 plants against 17 cattle diseases in some rural villages of Ganjam district of Orissa, including few plants used for milching of cattle are described
Fuel wood burning and its effect on the environment with Reference to tribal villages of Bolangir, Orissa, India
Studies on air pollution due to burning of fuel wood for cooking purpose is alarming day by day in the tribal villages of Bolangir Dist. of Orissa. About 85 household are selected for the study, which burn about 254 tonn...
Biological activity of biobras and Pectimorf-6 in each of the phases of micropropagation of banana (Musa sp.)
The use of biotechnology in the propagation of plantain and banana (Musa sp.) of great importance to induce, tolerant to plant genotypes for diseases and high yield potentials. However, auxins and cytokinins should be us...
Characterization of silica nanoporous structures of freshwater diatom frustules
A phytoplanktonic unicellular alga known as diatoms belonging to the class Bacillariophyceae, possess a distinct, highly ornamented siliceous cell wall consisting of two overlapping halves. Diatoms are found both in mari...