ANTI-DIABETIC POTENTIAL OF PEPTIDE FROM P. NIRURI REVEALS THROUGH CARBOHYDRATE HYDROLYZING ENZYME INHIBITION ASSAY
Journal Title: Science Heritage Journal | Galeri Warisan Sains (GWS) - Year 2019, Vol 3, Issue 1
Abstract
Herb Phyllanthus niruri (P. niruri) is known to have various pharmacological functions including anti-diabetic properties. In this research, protein extracts from different plant parts (leave, fruit and stem) of P. niruri were investigated for their anti-diabetic potential through α-amylase and α-glucosidase enzyme inhibition assays. For the enzyme inhibition assay, fruit was found to have the highest inhibition percentage (90.0%) against α-glucosidase followed by leave (62.6%) and stem (38.4%). The similar patterns were also recorded for the α-amylase enzyme inhibition assay, in which, fruit showed the highest inhibition percentage (64.1%) followed by leave (33.3%) and stem (18.2%). The findings of this research suggest that fruit of P. niruri is a potential plant part with regards to anti-diabetic properties since it exhibits the highest inhibition activity against both α-amylase and α-glucosidase enzyme compared to leave and stem.
Authors and Affiliations
Noor Hasniza Md Zin, Ainul Mardhiah Mohd Nail
Keywords
Related Articles
- EP ID EP488001
- DOI 10.26480/gws.01.2019.17.19
- Views 78
- Downloads 0
IN-VITRO REGENERATION OF ORTHOSIPHON STAMINEUS (MISAI KUCING) USING AXILLARY BUD
Orthosiphon stamineus or known as Misai kucing is a popular herbal tea plant that helps in treating the ailments of kidney and bladder, diabetes mellitus and gout. Due to high demand of this medicinal plant, a large prop...
The investigation of cytotoxic effect of cinnamomum zeylanicum extracts on human breast cancer cell line (mcf-7)
Cinnamon is one of the oldest herbal medicine that has been historically known to possess has anticancer property. In this study, the cytotoxicity of the cinnamon extracts towards human breast cancer cell line (MCF-7) wa...
Noise exposure during orthopaedics surgery
There is serious concern on noise hazard in operating theatre especially in the orthopaedics field that requires usage of many instruments. However, data on this noise exposure particularly in Malaysia is rather limited....
LEAF ANATOMY AND MICROMORPHOLOGY OF SELECTED PLANT SPECIES IN COASTAL AREA OF KUANTAN, PAHANG, MALAYSIA
Plant anatomy can play vital role in plant taxonomy for successfully resolve taxonomic problems among different plant species. The anatomical studies of plant species living in coastal area of Kuantan, Pahang are scarce....
Isolation and characterization of biosurfactant producing bacteria isolated from petroleum contaminated sites with the potential to be used in bioremediation
Surfactants have been widely used to facilitate biodegradation of petroleum pollutant; particularly those are being produced by microorganisms which are also known as biosurfactant. Six bacterial isolates from petroleum...