ANTI FUNGAL COMPOUNDS FROM MARINE STREPTOMYCES
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 1
Abstract
Objective: To identify antifungal compounds from marine Streptomyces.Methods: Strptomyces were isolated from marine soil sample by the spread plate method. From the active strain crude compounds were extracted by the solvent extraction method. Crude compounds were purified by TLC method. Then the identification of compounds done by GC-MS analysis.Results: One of the active strain was identified as Streptomyces rubralavendulae strain SU1 (HQ234765). The antifungal compounds were shown resistant to Candida albicans. The antifungal compounds were identified by GC-MS as 2-Isopropyl-5-methyl-1-heptanol and Eicosane.Conclusion: These results could support the suggestion of Streptomyces as an alternative of the host for medicinal activity for treating fungal infections.Â
Authors and Affiliations
S. Usha Nandhini, P. Jaya Bharathy, S. Rekha
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