Anti-inflammatory and antioxidant activities of <i>cassia fistula linn</i> bark extracts
Journal Title: African Journal of Traditional, Complementary and Alternative Medicines - Year 2005, Vol 2, Issue 1
Abstract
Anti-inflammatory and Antioxidant activities of the aqueous (CFA) and methanolic extracts (CFM) of the [i]Cassia fistula[/i] Linn. bark were assayed in wistar albino rats. The extracts were found to posses significant anti-inflammatory effect in both acute and chronic models. [i]Cassia fistula[/i] bark extracts showed significant radical scavenging by inhibiting lipid peroxidation initiated by CCl[sub]4[/sub] and FeSO4 in rat liver and kidney homogenates. Both extracts exhibited significant antioxidant activity in DPPH, Nitric oxide and Hydroxyl radical induced invitro assay methods. Both extracts showed Dose-Dependent protective effect against lipid peroxidation and free radical generation in liver and kidney homogenates. Further, the acute toxicity study with the extracts showed no sign of toxicity up to a dose level of 2000 mg/ po. Thus it could be concluded that Cassia [i]fistula[/i] bark extracts (CFA & CFM) possess significant anti-inflammatory and anti oxidant properties.
Authors and Affiliations
Raju Ilavarasan, Moni Mallika, Subramanian Venkataraman
Keywords
Related Articles
- EP ID EP123477
- DOI -
- Views 100
- Downloads 0
OXYTOCIN-LIKE EFFECT OF HARPAGOPHYTUM PROCUMBENS DC [PEDALIACEAE] SECONDARY ROOT AQUEOUS EXTRACT ON RAT ISOLATED UTERUS
Harpagophytum procumbens DC [family: Pedaliaceae] is widely used in South African traditional medicine for the treatment, management and/or control of a variety of human ailments. Some traditional health practitioners of...
Healing effect on chronic gastric ulcers and short-term toxicity profile of the leaf methanol extract of <i>ocimum suave</i> wild (lamiaceae) in rats
The gastric cytoprotective actions of the extract of [i]Ocimum suave[/i] wild (lamiaceae) have previously been demonstrated. We have investigated here the healing effect of the leaf methanol extract of [i]Ocimum suave[/i...
IN VIVO ANTIMALARIAL AND CYTOTOXIC PROPERTIES OF ANNONA SENEGALENSIS EXTRACT
The in vivo animal antimalarial and in vitro cytotoxic activities of the methanol extract of Annona senegalensis Pers. (Annonaceae) was investigated in this study. The in vivo antimalarial activity of the methanol extrac...
Conservation of plant genetic resources
Survey, collection and conservation are important starting points in the genetic resources impact chain and in sustainable environmental protection strategies. Collection of plant genetic resources provides materials fo...
Piscicidal activity of alcoholic extract of nerium indicum leaf and their biochemical stress response on fish metabolism
Laboratory evaluations were made to asses the piscicidal activity of ethyl alcohol extract of Nerium indicum leaf against predatory fish Channa punctatus and their ultimate mode of action on fish metabolism. Toxicity ex...