Anti MDRSA activity of Rhizophora apiculata and Avicennia marina – An in-vitro study
Journal Title: International Journal of Allied Medical Sciences and Clinical Research - Year 2014, Vol 2, Issue 4
Abstract
A total of 100 Multi-drug resistant Staphylococcus aureus (MDRSA) strains, isolated from the clinical specimens received in the department of Microbiology, Rajah Muthiah Medical College, Annamalai University, Tamil Nadu, India, were subjected for screening of anti-MDRSA activity of the aqueous, ethanol and methanol extracts of the leaf part of the mangrove plants ie., Rhizophora apiculata and Avicennia marina with appropriate positive control (Amikacin). Agar well diffusion method was used in the in-vitro anti-bacterial assay to screen the crude extracts of the selected mangrove plant leaves. The study results revealed the promising anti-bacterial activity (anti-MDRSA) of the Rhizophora apiculata and Avicennia marina leaves’ crude extract against the MDRSA strains of the clinical sources. The low level anti-MDRSA activity was expressed by the aqueous extracts and the high level anti-MDRSA activity was shown by the ethanolic and methanolic extracts of Rhizophora apiculata and Avicennia marina respectively. From this we conclude and suggest that the ethanolic and methanolic extracts of these mangrove plant species can be preferred when one wants to perform an in-vitro anti-bacterial assay with the leaf extracts of Rhizophora apiculata and Avicennia marina, and can avoid testing with the aqueous extract by which one can save time, energy and economy and the Rhizophora apiculata and Avicennia marina leaves may be considered as one of the major sources for the production of the effective drugs to control the multi-drug resistant infections with MDRSA strains.
Authors and Affiliations
Kavitha K K
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