Anti-MRSA studies on active extracts from Tridax procumbens L.
Journal Title: GJRA-Global Journal For Research Analysis - Year 2015, Vol 4, Issue 2
Abstract
The study was intended for the therapeutic management of methicillin resistant Staphylococcus aureus by the use of medicinal plant Tridax procumbens. A total of 472 clinical isolates of Staphylococcus aureus were included for the study. Anti-MRSA screening was done for methicillin resistance based on Kirby-Bauer disk diffusion method using oxacillin (1μg) and methicillin (5μg) discs. Antibacterial activity of MRSA was assayed using 20 different extracts obtained from polar and non-polar solvents. The significant inhibition zone range of 17-23 mm was obtained from methanol root extracts. The antibiotic susceptibility testing of S. aureus isolates revealed high degree of resistance (94.82%) to penicillin and ampicillin, while 5.17% isolates were sensitive to both antibiotics. The study concludes that, the screening of anti-MRSA potential of medicinal plants would help to rediscover the new therapeutic plant drugs for the management of emerging strains of the common pathogen.
Authors and Affiliations
V. A. Kamble, A. H. Moon
Keywords
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