Anti-Mycobacterium Metabolite from Marine Sponge Iricinia fusca
Journal Title: Journal of Pharmaceutical Research International - Year 2017, Vol 15, Issue 4
Abstract
Chemical investigation of the marine sponge Ircinia fusca leads to isolation of a new pyrrole derivative (1) and two known compounds namely, 3 methyl decanoic acid (2) and Benzenedicarboxylic acid (3). The structures of compounds were established by 1D and 2D NMR and MS data. Compound 1 exhibited strong antibacterial activity against Mycobacterium smegmatis at MIC 116 μM. Compounds 1-3 showed neither antifungal nor cytotoxic activity.
Authors and Affiliations
Srinu Meesala, Ruby Singh, Milind G. Watve
Keywords
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- EP ID EP313058
- DOI 10.9734/BJPR/2017/32881
- Views 109
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