Anti Synthetase Syndrome – A Case Report
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 8
Abstract
Anti-synthetase syndrome (ASS) has been recognized as an important cause of autoimmune inflammatory myopathy in a subset of patients with polymyositis and dermatomyositis. Its hallmark is thepresence of serum antibodies to aminoacyl-transfer RNA synthetases and is characterized by a constellation of manifestations. Clinicians should be familiar with this entity. There is favourable response to steroids and immunosuppressants. We describe here a case of ASS presenting with myositis, interstitial lung disease(ILD), fever, deforming arthritis and Raynaud’s phenomenon who had high titre of anti jo-1antibodies.The patient responded well to steroids and cyclophosphamide pulse.
Authors and Affiliations
Dr. Nilom Khound, Dr. MrinalCh. Bhattacharyya, Dr. BhaskarJyoti Kakati
Keywords
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- EP ID EP380731
- DOI 10.9790/0853-1708010611.
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