Anti TNF tedavisi seyrinde gelişen üveitler: primer hastalıktan mı ilaçtan mı?
Journal Title: Ege Tıp Dergisi - Year 2019, Vol 58, Issue 0
Abstract
Anti-TNF ilaçlar, non-enfeksiyoz üveit için günümüzde etkinliği kanıtlanmış yaygın kullanılan tedavilerdir. Mevcut tüm anti-TNF ilaçların üveit tedavisinde olumlu etkileri bildirilmiştir. Ancak retrospektif ve gözlemsel çalışmalarda etanersept tedavisi sonrası düşük etkinlik veya paradoksal etkiye bağlı olarak üveit gelişimi bildirilmiştir. Paradoksal reaksiyonlar, Anti-TNF tedavisi sırasında, bu ilaca bağlı olarak gelişen ve genellikle bu grup ilaçlara yanıt veren patolojik durumlar olarak tanımlanır. Paradoksik üveit tedavisini, hastaların altta yatan hastalığının ve üveitin durumları ve hastanın demografik verileri belirlemelidir.
Authors and Affiliations
Didem Arslan
Keywords
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