ANTIBACTERIAL ACTIVITY DIFFERENCE IN SINGLE AND GRADIENT EXTRACTIONS OF LITSEA LIGUSTRINA (NEES) HOOK. F.
Journal Title: Journal of Biological and Scientific Opinion - Year 2016, Vol 4, Issue 2
Abstract
Leaves of Litsea ligustrina (Nees) Hook.f. (Lauraceae) evaluated for its antibacterial activity in 80% ethanolic extract and compared with its activity in gradient extraction using various solvents of increasing polarity. Litsea ligustrina showed a prominent antibacterial activity towards all the nine strains of bacteria in ethanolic extract. Antibacterial principle isolation is usually done in a process starting with gradient extraction. Antibacterial study of L. ligustrina was done using petroleum ether, acetone and ethanol as extracting solvents in the gradation of increasing polarity. However, these solvent extracts didn’t show any antibacterial activity. From this result it was inferred that, antibacterial activity of L. ligustrina exhibited in ethanol extract might be due to some heat liable compounds which may be lost during drying process and powdering. Preliminary phytochemical evaluation revealed the presence of alkaloids, phenolics and flavonoids in L. ligustrina which may be the reason for its antibacterial activity. But there may be some heat liable compounds which may be lost during processing which may cause some reduction in antibacterial activity.
Authors and Affiliations
Angeline Cyriac , Toji Thomas
Keywords
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- EP ID EP143846
- DOI 10.7897/2321-6328.04210
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