Antibacterial activity of honey alone and in combination with Nigella sativa seeds against Pseudomonas aeruginosa infection
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2012, Vol 2, Issue 0
Abstract
Objective: To evaluate the in vitro activities, of three honeys sample, and Nigella sativa (N. sativa) against Pseudomonas aeruginosa (P. aeruginosa) alone and in combination. Methods: The antibacterial test and minimum inhibition concentration (MIC) was determined by using agar well diffusion and dilution methods respectively against P. aeruginosa. Results: The MIC for the three varieties of honey without N. sativa against P. aeruginosa ranged between 46% and 50% (v/v). Addition of N. sativa (8%) resulted in synergistic bactericidal activity. An MIC drop was noticed with each variety and it ranged between 77.77% and 84.21%. Conclusions: These antibacterial properties would warrant further studies on the clinical applications of N. sativa and honey against P. aeruginosa.
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- EP ID EP233639
- DOI 10.1016/S2222-1808(12)60197-2
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