ANTIBACTERIAL ACTIVITY OF SELECTED MEDICINAL PLANT IN TRADITIONAL TREATMENT OF WOUND INFECTION IN SOUTHEAST INDIA
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 11
Abstract
Objective: The wound healing potential of fruit peel of Pithecellobium dulce Benth, a plant traditionally used for wound treatment against wound- infecting bacteria, was assessed using disc diffusion and microtitre plate methods.Methods: P. dulce fruit peel was extracted using ethyl acetate, methanol and water and tested for their antimicrobial activities against bacterial isolates from wound infection using disc diffusion and microtitre plate methods.Results: All the three extracts had antimicrobial activities, among which methanol extract had higher activities against all the tested organisms compared to the ethyl acetate and aqueous extracts. The most susceptible organism to all the extracts was K. pneumonia and S. aureus while the most resistant were P. mirabilis and P. vulgaris. Conclusion: The potential antibacterial activity of P. dulce plant against both gram-positive and gram-negative bacteria justifies the use of the plant as the wound healing agent. The isolation of active principle of this plant may serve as source and lead for the synthesis of drugs in pharmaceutical industries.Â
Authors and Affiliations
Sukantha T. A. , Shubashini K. Sripathi, Ravindran N. T.
COMPUTATIONAL INTERACTION OF ENTOMOPATHOGENIC FUNGAL SECONDARY METABOLITES WITH PROTEINS INVOLVED IN HUMAN XENOBIOTIC DETOXIFICATION
Objective: Entomopathogenic fungi are rich source of secondary metabolites which posses both pharmacological and insecticidal activity. It is essential to assess metabolite toxicity of chemically diverse toxic metabolite...
DEVELOPMENT OF NEW PYRAZOLE HYBRIDS AS ANTITUBERCULAR AGENTS: SYNTHESIS, BIOLOGICAL EVALUATION AND MOLECULAR DOCKING STUDY
Objective: synthesis of new 1, 3-diphenyl pyrazole derivatives 9(a-f) and 10(a-f) using molecular hybridization approach for antitubercular and cytotoxic studies.Methods: The structures of synthesized compounds were conf...
EVALUATION OF IN VITRO ANTICANCER POTENTIAL OF ETHANOLIC EXTRACT AND ITS DIFFERENT FRACTIONS OF CAESALPINIA BONDUC (L) ROXB SEEDS
Objective: The present study aims to evaluate the anticancer potential of ethanolic extract and its different fractions of Caesalpinia bonduc seeds against Ehrlich Ascites Carcinoma (EAC) cell lines.Methods: Ethanolic ex...
QUANTIFICATION OF PHYTOCHEMICAL CONTENTS AND IN VITRO ANTIOXIDANT ACTIVITY OF EXACUM BICOLOR (ROXB.), AN ENDEMIC MEDICINAL PLANT
Objective: To investigate different phytochemical contents and screening of antioxidant activity of sequentially extracted Exacum bicolor leaf with different solvents.Methods: Leaf samples of E. bicolor were dried and su...
ANTI-PROLIFERATIVE ACTIVITIES OF PURIFIED BACTERIOCIN FROM ENTEROCOCCUS MUNDTII STRAIN C4L10 ISOLATED FROM THE CAECUM OF MALAYSIAN NON-BROILER CHICKEN ON CANCER CELL LINES
Objective: This study aim at experimenting the effects of the bacteriocin from Ent. mundtii strain C4L10, an apoptogenic properties, that have the ability to inhibit bacteria at the same time the tendency to induce anti-...