Abstract

Objective: The study of marine organisms for their bioactive potential, being an important part of marine ecosystem has picked up the rhythm in recent years with the growth recognition of their importance in human life as well as animals. Methods: In this present study ethanol, methanol and acetone extract of two gastropods Conus betulinus and Conus inscriptus were assayed for the antibacterial activity against three poultry bacterial pathogens. Results: The antibacterial activity of Conus betulinus tissue extract, showed maximum zone of inhibition (15mm) against Salmonella pullorum and minimum activity (4 mm) was observed in Salmonella typhimurium. In Conus inscriptus, the tissue extract showed the maximum zone of inhibition (12mm) against S. enteritidis and minimum activity (3 mm) was observed in S. pullorum. Molecular size of muscle protein was determined using Sodiumdodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). FTIR analysis reveals the presence of bioactive compounds signals at different ranges. Conclusions: Among the two gastropods, Conus betulinus showed more antibacterial activity than that of Conus inscriptus. The reveled in this research shows that gastropod Conus betulinus tissue is medicinal value due to high quality of antibacterial compounds.

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