Antibacterial and Antifungal Activity of Methanolic Leaf Extract of Allium sativum on Selected Pathogenic Strains

Journal Title: International Journal of TROPICAL DISEASE & Health - Year 2014, Vol 4, Issue 11

Abstract

Allium sativum plants contain chemicals which can inhibit the growth of microorganisms and thus make them suitable to be used in different medicines. The antibacterial and antifungal activities of Allium sativum methanolic extracts were investigated using standard analytical techniques and modern micro plate-based antibacterial assays techniques. The antibacterial of methanolic extract of Allium sativum were used on different bacteria strains which include Escherichia coli, Pseudomonas aeruginosa, Protea spp., Salmonella typhi and Staphylococcus aureus. The antifungal observation of Allium sativum was found to be active against Aspergilus flavus, Aspergilus niger, Aspergilus fumigatus, Penicillium spp compared to Funbact-A (control). The susceptibility test showed that Allium sativum is more active against Aspergilus fumigatus. The Allium sativum had a higher zone of inhibition compared to Ciproflaxin (control) on the different bacteria strains. Aspergillus fumigatus and Aspergillus niger differs significantly in their degree of inhibition of methanolic extract of Allium sativum. The findings support the use of Allium sativum extract in treating bacterial infections and Aspergillosis.

Authors and Affiliations

Osheke Shekins Okere, Janet Olayemi Sangodele, Moses Dele Adams, Eunice Ogunwole, Mercy Omoye Shafe

Keywords

Related Articles

Malaria Treatment Patterns among Patent Medicine Vendors in Obio-Akpor Local Government Area of Rivers State, Nigeria

Aims: Patent medicine vendors are patronized by people from all segments of the community because they are perceived to be more accessible, caring, and less expensive than public health facilities. However, cases of poor...

Hepcidin: A New Noninvasive Biomarker for Histological Cirrhosis in Hepatitis C Virus Patients

Aim: To investigate the potential role of serum hepcidin as a biomarker for histological cirrhosis in hepatitis C virus patients. Methods: Serum hepcidin was measured in 80 patients with hepatitis C virus and 15 age and...

Pattern and Outcome of Higher Order Caesarean Section in a Tertiary Health Institution in Nigeria

Objective: To determine the rate, pattern and outcome of higher order caesarean section (HOCS) in a tertiary health facility. Materials and Methods: A retrospective study of 182 women who had undergone three or more caes...

High Prevalence of Hypocholesterolaemia among Antiretroviral Therapy-naive HIV-infected Children in Makurdi, Nigeria: A Retrospective Study

Aim: To determine the abnormalities in total cholesterol (TC) levels and the potential risk factors in ART–naive, HIV-infected Nigerian children. Study Design: A retrospective and cross-sectional study. Place and Duratio...

Perceived Training Needs of Butchers and Meat Retailers Regarding Meat Handling Practices in Jammu District of Jammu and Kashmir

The hygienic meat handling practices of the butchers and meat retailers, and hygienic status of slaughterhouses and the surrounding are of great importance for both the meat handlers and the consumer. In order to enhance...

Download PDF file
  • EP ID EP343388
  • DOI 10.9734/IJTDH/2014/11611
  • Views 81
  • Downloads 0

How To Cite

Osheke Shekins Okere, Janet Olayemi Sangodele, Moses Dele Adams, Eunice Ogunwole, Mercy Omoye Shafe (2014). Antibacterial and Antifungal Activity of Methanolic Leaf Extract of Allium sativum on Selected Pathogenic Strains. International Journal of TROPICAL DISEASE & Health, 4(11), 1146-1152. https://europub.co.uk/articles/-A-343388