Antibacterial Efficacy of Collagen and Foetal Barrier Membranes
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 8
Abstract
Introduction: A wide range of barrier membranes are used in guided tissue and bone regeneration for reconstructing lost periodontium. One of the main reasons for unsuccessful regenerative procedures is the colonization and penetration of bacteria through barrier membrane into the treated site. Certain bacteria have high adherence to GTR membranes with periodontal pathogens showing greater affinity. Antibacterial properties of amniotic fluid are well documented and demonstrated. No such factors have yet been found in amniotic membranes. The antibacterial activity if present in GTR membranes can control inflammatory lesion and collagenolytic activity of bacteria increasing the life of the membrane and treatment outcome. Study aimed to investigate the antibacterial properties of collagen and foetal barrier membranes. Material and methods: Three membranes (Collagen, Chorion, Amnion) were tested against three bacterial strains (S. aureus, A. actinomycetemcomitans, P. gingivalis) using direct contact test. The optical densities of bacterial growth were evaluated using Spectrophotometry. Results: There was no statistical significant difference in the growth of bacteria for Amnion and Collagen membrane. However there is a statistically significant increased growth of P. gingivalis and A. actinomycetemcomitans on Chorion membrane. Conclusions: Thus chorion membrane enhances the growth of periopathogens in vitro and maybe a potential risk to regeneration.
Authors and Affiliations
Prutha Vaidya, Pallavi Badade, Alisha Panjwani, Agraja Patil, Ayushya Warang, Swapna Mahale
Keywords
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