ANTIBACTERIAL POTENTIAL OF CRUDE METHANOLIC EXTRACT OF Leonotis nepetifolia (L) R. Br
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 2
Abstract
The methanolic extract of leaf, flower and stem of Leonotis nepetifolia was analyzed for antibacterial activity against eight pathogenic bacterial isolates viz., Escherichia coli, Pseudomonas aeruginosa, Shigella dysenteriae, Shigella flexneri, Vibrio cholerae, Bacillus subtilis, Micrococcus luteus and Saphylococcus aureus. The extract was also subjected to qualitative tests for alkaloids, tannins, terpenoids, steroids, saponins and flavonoids. The methanolic extract exhibited antibacterial activity against all the bacteria tested indicating the presence of broad spectrum antibacterial compounds in the plant parts. Gram positive bacteria were found to be more susceptible than Gram negative bacteria. The leaf and flower extract of the plant showed higher activity than the stem. Phytochemical examination indicated the presence of alkaloids, saponins, tannins and terpenoids.
Authors and Affiliations
Sankar Sinha
Keywords
Related Articles
- EP ID EP119569
- DOI -
- Views 105
- Downloads 0
BIOACTIVE AND NUTRACEUTICAL COMPOUND MANIPULATION IN HIBISCUS SABDARIFFA L. LEAVES: A COMMON UNDERSHRUB CONSUMED BY THE BODO TRIBES OF BTC, ASSAM, INDIA
Hibiscus sabdariffa L. is a gregarious under shrub, which is traditionally consumed by the Bodo tribes of Assam, India as a major constituent of food. Ethno medicinally the leaves, flowers and fruits are used for stomach...
ANTIINFLAMMATORY EFFECT OF AQUEOUS EXTRACT OF MILLINGTONIA HORTENSIS LINN.F STEM BARK ON RATS
Millingtonia hortensis Linn.F (Bignoniaceae) is found throughout south Asia for its fragrant flowers. The present study aims at exploring the antiinflammatory potential of the stem bark of the tree. Aqueous extract...
DRUG UTILIZATION PATTERN IN PATIENTS WITH CONGESTIVE CARDIAC FAILURE IN A SOUTH INDIAN TERTIARY CARE HOSPITAL: A RETROSPECTIVE STUDY
Drug utilization studies are the powerful exploratory tools to ascertain the role of drugs in determining the therapeutic efficacy, cost effectiveness and minimizing the adverse effects. In our study, we have attempted t...
COBROTOXIN ASSOCIATED WITH HIGH PHOSPHOLIPASE A2 ACTIVITY DISCOVERED FROM THE VENOM OF Naja naja (INDIAN COBRA)
A toxin with high in vitro neurotoxicity and Phospholipase A2 activity has been isolated from the venom of the Naja naja (Indian cobra) by column chromatography.
PRELIMINARY EVALUATION OF THE PROPERTIES OF BIOMATERIAL OF TYMPANOTONUS FUSCATA SHELL AS PHARMACEUTICAL EXCIPIENT
Tympanotonus fuscata var radula (L) or periwinkle is a mollusc and abounds in the Niger Delta, Nigeria. It is highly consumed as source of protein. The empty shells, hither to poorly utilized add to environmental menace....