Antibiofilm Potential of Metal Based Nanoparticles: Synthesis and Mode of Action
Journal Title: JOURNAL OF MULTIDISCIPLINARY RESEARCH IN HEALTHCARE - Year 2018, Vol 4, Issue 2
Abstract
Biofilm refers to a group of microbes colonizing together and often adhered to a surface. The adherence is attributed to secretion of polymeric substances comprising of extracellular DNA, proteins, and polysaccharides thereby limiting the access and inhibitory activity of existing antimicrobial agents. Biofilm are a major cause of acute infections and pose immense clinical threat especially in conditions employing the use of invasive devices thus being a major source of mortality and morbidity. Hence there is a dire need to develop alternative treatment against biofilm-related infections. Advances in nanotechnology has opened new horizons. Nanoparticles derived from various metal present promising candidates to ameliorate biofilms owing to their antioxidant potential.
Authors and Affiliations
R Kaur , M Khurana, R K Virk , A Sharma
Keywords
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- EP ID EP596663
- DOI 10.15415/jmrh.2018.42006
- Views 143
- Downloads 0
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