Antibiogram of Vulvovaginal Candidiasis amongst Pharmacy Undergraduates in a Nigerian University
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 22, Issue 12
Abstract
Objectives: To assess the knowledge, perception, incidence and the antibiogram of vulvovaginal candidiasis (VVC). Methods: Validated questionnaires were used to collect demographic information of consenting study participants and to test the participants’ level of knowledge and perception of VVC among pharmacy undergraduates. High-vaginal swab specimens were also collected for isolation of Candida species and speciation using standard yeast identification protocol and CHROMagar respectively. Results: Among the 160 participants, yeasts were detected in 43.75% and 27.50% by culture and direct microscopy respectively. Having multiple sexual partners (at least two), poor vaginal hygiene and antibiotic usage were shown to significantly increase the incidence of VVC (p<0.05). Yeasts other than Candida albicans were predominant (66.67%), especially Candida tropicalis (40.00%). Although participants’ knowledge about VVC was good (80.49%), their perception was only average (54.10%). Susceptibility test showed that the isolates were susceptible to voriconazole (84.37 ± 5.70%), fluconazole (71.54 ± 7.66%) and nystatin (65.70 ± 12.33%). The commonest isolate (Candida tropicalis) was farely susceptible to voriconazole (77.00%) and fluconazole (63.00%) but resistant to nystatin (36.00%). Conclusion: There is high prevalence of VVC despite good knowledge and average perception. Candida tropicalis was predominant in the study. Based on antibiogram, Voriconazole was the most effective drug/antibiotic and drug of choice for therapy.
Authors and Affiliations
Angus N. Oli, Chiamaka B. Ugwu, Eunice O. Osuala, Charlotte Blanche Oguejiofor, George Uchenna Eleje, Felix N. Osuala, Malachy C. Ugwu
Keywords
Related Articles
- EP ID EP311986
- DOI 10.9734/JAMMR/2017/33340
- Views 48
- Downloads 0
The In vitro Effects on Platelet Functions and Coagulation of Different Prime Solutions Used in Cardiopulmonary by Pass
Purpose: To investigate the in vitro effect of human albumin (HA) and fresh frozen plasma (FFP) added to prime solution on platelet functions and coagulation in patients undergoing cardiopulmonary bypass (CPB) surgery. M...
The Incidence of Hypersplenism in Decompensated Liver Cirrhosis of Alcoholic Etiology
Introduction: Liver cirrhosis is a terminal, morpho-functional entity of hepatic dysfunction, which is characterized by the replacement of the hepatic lobule connective tissue nodules. Splenomegaly is a common finding in...
Knowledge and Attitude of Diabetic Patients towards the Oral Complications of Diabetes Mellitus and Factors Associated with Their Knowledge in Khartoum State, Sudan
Background: Diabetes Mellitus is a chronic long term condition, affecting all age groups. Uncontrolled diabetes can lead to serious oral complications ranging from acute to chronic, which manifest in several ways and can...
High Prevalence of Malnutrition among the Above Thirteen with Primary Pyomyositis in Northern Uganda
Aim: To determine the prevalence of malnutrition and its association with primary pyomyositis among patients and controls who were age and sex matched. Study Design and Setting: A case-control study was conducted at Gulu...
Severe Hypokalaemia as a Cause of Reversible Diabetes Mellitus
Aims: To discuss the likelihood of severe hypokalaemia as a cause of reversible diabetes. Presentation of the Case: A 46 year old patient presented to the Accident and Emergency unit (A&E) with a history of polyuria an...